ENCH482-15S1 (C) Semester One 2015

Bioprocess Engineering 2

15 points

Details:
Start Date: Monday, 23 February 2015
End Date: Sunday, 28 June 2015
Withdrawal Dates
Last Day to withdraw from this course:
  • Without financial penalty (full fee refund): Friday, 6 March 2015
  • Without academic penalty (including no fee refund): Friday, 22 May 2015

Description

Bioreactor design and operation including bacteria, yeast and tissue culture, formulation, bioseparations.

Topics

Dr. Gabriel Visnovsky:  14 lectures
Animal cell culture: uses and applications in industry and biotechnology
                             
• Introduction and history.
• Design and requirements for setting up an animal cell culture lab.
• Security in the lab.
• Animal cell culture characteristics and requirements.
• Quality control
• General techniques and systems for cultivation animal cell culture
• Factors influencing cell growth
• Kinetics and metabolic yield coefficients
• Strategies for production process design. Lab, pilot, and large scale: CSTR vs. ALR
• Biotechnological applications: Production of secondary vaccines and metabolites: bacteria vs. animal cell cultures systems, advantages and disadvantages
• Case Study I: Production of Baculovirus in large scale airlift  reactors using insect cells
• Case Study II: Development, optimisation and scale up of a biotechnological process to produce Oryctes virus.


Dr. Simone Dimartino: 12 lectures

Biomimetics and Biomaterials

The biomimetic engineering part will entail a field trip to the Kaikoura field station on 12-14th April 2015. The field trip is not compulsory but recommended to help complete the research project.


• Introduction to biomimetics
• Natural and nature-inspired biomaterials
• Systems for drug delivery
• Lessons from Nature in regenerative medicine
• Surface aspects: super-hydrophobic surfaces and bio-adhesion


Prof. Conan Fee: 10 lectures

Bioseparations and Chromatography

• Bioproducts
• Review of biological molecule properties (emphasis on proteins)
• General bioseparation principles
• Process scale protein chromatography
• Adsorption isotherms
• Bioseparation strategies
• Optimisation and scale-up

Prerequisites

ENGR407 or ENCH323

Course Coordinator / Lecturer

Gabriel Visnovsky

Lecturers

Simone Dimartino and Conan Fee

Assessment

Assessment Due Date Percentage 
Final Exam 42%
Assignment 27 Mar 2015 10%
Presentation 06 May 2015 15%
Report 14 May 2015 18%
Report 04 Jun 2015 15%

Indicative Fees

Domestic fee $988.00

International fee $4,725.00

* All fees are inclusive of NZ GST or any equivalent overseas tax, and do not include any programme level discount or additional course-related expenses.

For further information see Chemical and Process Engineering .

All ENCH482 Occurrences

  • ENCH482-15S1 (C) Semester One 2015
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