Timothy Allison

LecturerTimothy Allison

Chemistry Seminar Co-ordinator
Beatrice Tinsley 328
Internal Phone: 93034

Qualifications & Memberships

Research Interests

I investigate how proteins work and assemble using chemical and structural biology approaches incorporating native mass spectrometry and protein crystallography. I have a particular interest in the enzymes involved in glycan biosynthesis, and alongside this, fundamental interests in the technical workings of the methodologies I employ.

Recent Publications

  • Yen HY., Abramsson ML., Agasid MT., Lama D., Gault J., Liko I., Kaldmäe M., Saluri M., Qureshi AA. and Suades A. (2022) Electrospray ionization of native membrane proteins proceeds via a charge equilibration step. RSC Advances 12(16): 9671-9680. http://dx.doi.org/10.1039/d2ra01282k.
  • Sahin C., Österlund N., Leppert A., Johansson J., Marklund EG., Benesch JLP., Ilag LL., Allison TM. and Landreh M. (2021) Ion mobility-mass spectrometry shows stepwise protein unfolding under alkaline conditions. Chemical Communications 57(12): 1450-1453. http://dx.doi.org/10.1039/d0cc08135c.
  • Allison TM. and Agasid MT. (2020) Native Protein Mass Spectrometry. Methods in Molecular Biology: 287-299. http://dx.doi.org/10.1007/978-1-4939-9869-2_15.
  • Allison TM., Barran P., Benesch JLP., Cianferani S., Degiacomi MT., Gabelica V., Grandori R., Marklund EG., Menneteau T. and Migas LG. (2020) Software Requirements for the Analysis and Interpretation of Native Ion Mobility Mass Spectrometry Data. Analytical Chemistry 92(16): 10881-10890. http://dx.doi.org/10.1021/acs.analchem.9b05792.
  • Allison TM., Barran P., Cianférani S., Degiacomi MT., Gabelica V., Grandori R., Marklund EG., Menneteau T., Migas LG. and Politis A. (2020) Computational Strategies and Challenges for Using Native Ion Mobility Mass Spectrometry in Biophysics and Structural Biology. Analytical Chemistry 92(16): 10872-10880. http://dx.doi.org/10.1021/acs.analchem.9b05791.