Timothy Allison

Senior LecturerTimothy Allison

Chemistry Seminar Co-ordinator
Beatrice Tinsley 328
Internal Phone: 93034

Qualifications & Memberships

Research Interests

I investigate how proteins work and assemble using chemical and structural biology approaches incorporating native mass spectrometry and protein crystallography. I have a particular interest in the enzymes involved in glycan biosynthesis, and alongside this, fundamental interests in the technical workings of the methodologies I employ.

Recent Publications

  • Allison TM., Degiacomi MT., Marklund EG., Jovine L., Elofsson A., Benesch JLP. and Landreh M. (2022) Complementing machine learning-based structure predictions with native mass spectrometry. Protein Science 31(6) http://dx.doi.org/10.1002/pro.4333.
  • Yen HY., Abramsson ML., Agasid MT., Lama D., Gault J., Liko I., Kaldmäe M., Saluri M., Qureshi AA. and Suades A. (2022) Electrospray ionization of native membrane proteins proceeds via a charge equilibration step. RSC Advances 12(16): 9671-9680. http://dx.doi.org/10.1039/d2ra01282k.
  • Abramsson ML., Sahin C., Hopper JTS., Branca RMM., Danielsson J., Xu M., Chandler SA., Österlund N., Ilag LL. and Leppert A. (2021) Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry.. JACS Au 1(12): 2385-2393. http://dx.doi.org/10.1021/jacsau.1c00458.
  • Sahin C., Österlund N., Leppert A., Johansson J., Marklund EG., Benesch JLP., Ilag LL., Allison TM. and Landreh M. (2021) Ion mobility-mass spectrometry shows stepwise protein unfolding under alkaline conditions. Chemical Communications 57(12): 1450-1453. http://dx.doi.org/10.1039/d0cc08135c.
  • Allison TM. and Agasid MT. (2020) Native Protein Mass Spectrometry. Methods in Molecular Biology: 287-299. http://dx.doi.org/10.1007/978-1-4939-9869-2_15.