Timothy Allison

LecturerTimothy Allison

Chemistry Seminar Co-ordinator
Beatrice Tinsley 328
Internal Phone: 93034

Qualifications & Memberships

Research Interests

I investigate how proteins work and assemble using chemical and structural biology approaches incorporating native mass spectrometry and protein crystallography. I have a particular interest in the enzymes involved in glycan biosynthesis, and alongside this, fundamental interests in the technical workings of the methodologies I employ.

Recent Publications

  • Allison TM. and Bechara C. (2019) Structural mass spectrometry comes of age: New insight into protein structure, function and interactions. Biochemical Society Transactions 47(1): 317-327. http://dx.doi.org/10.1042/BST20180356.
  • Collier MP., Reid Alderson T., De Villiers CP., Nicholls D., Gastall HY., Allison TM., Degiacomi MT., Jiang H., Mlynek G. and Fürst DO. (2019) HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C. Science Advances 5(5) http://dx.doi.org/10.1126/sciadv.aav8421.
  • Kaldmäe M., Österlund N., Lianoudaki D., Sahin C., Bergman P., Nyman T., Kronqvist N., Ilag LL., Allison TM. and Marklund EG. (2019) Gas-Phase Collisions with Trimethylamine-N-Oxide Enable Activation-Controlled Protein Ion Charge Reduction. Journal of the American Society for Mass Spectrometry 30(8): 1385-1388. http://dx.doi.org/10.1007/s13361-019-02177-8.
  • Bolla JR., Sauer JB., Wu D., Mehmood S., Allison TM. and Robinson CV. (2018) Direct observation of the influence of cardiolipin and antibiotics on lipid II binding to MurJ. Nature Chemistry 10(3): 363-371. http://dx.doi.org/10.1038/nchem.2919.
  • Gault J., Lianoudaki D., Kaldmäe M., Kronqvist N., Rising A., Johansson J., Lohkamp B., Laín S., Allison TM. and Lane DP. (2018) Mass Spectrometry Reveals the Direct Action of a Chemical Chaperone. Journal of Physical Chemistry Letters 9(14): 4082-4086. http://dx.doi.org/10.1021/acs.jpclett.8b01817.