Novel chromatographic stationary phases for bio-separations:
This project aims to study a new convective chromatographic support (Capillary Channelled Polymers, C-CP) for the purification of proteins and other large biomolecules. C-CP fibres represent a promising alternative to traditional packed columns, as they are endowed with high separation performances unaffected by flow rate, optimal mass transport properties and a flexible surface that can be easily functionalized with a range of chromatographic ligands. This matrix is presently investigated to open novel and cost-effective purification strategies for the production of biopharmaceuticals
Wet-resistant bio-inspired adhesives:
Biological adhesives offer impressive performances in their natural context and have the potential to inspire novel, superior industrial adhesives for an increasing variety of high-tech applications. Goal of this project is to develop underwater biological adhesive inspired from marine organisms, with a particular focus on kelps and seaweed. The present research activities focus on the chemical and structural characterization of the adhesive secreted by New Zealand native seaweed species. A range of different experimental techniques are used to this aim, e.g. colorimetric assays, zeta potential measurements, cell cultures of seaweed propagules and Attenuated Total Reflection - Fourier Transform Infrared Spectroscopy, ATR-FTIR.