Dr Gabriel Alberto Visnovsky

Chemical and Process Engineering

Fields of Research

  • Biotechnology
  • Biochemical engineering
  • Bioprocess engineering and optimisation
  • Fermentation and bioreactor design
  • Insect cell culture and baculovirus expression vector system
  • High cell density cultures of animal cells and microorganisms
  • Algae, cell plant and hairy root culture
  • Environmental biotechnology

Researcher Summary

My current research is focussed in the development of industrial processes for the production of large-scale, high cell density cultures of bacteria and fungi for their use as biological control agents or for their valuable secondary metabolites. An important part of this research is in understanding and manipulating the variables that play a key role in the production process, the relationships between them and how these influence on the whole process. Examples of these variables are: strain selection, culture medium development, optimisation of the fermentation conditions, bioreactor selection, design and operation, fermentation strategy, bioprocess stoichiometry and bioprocess design.

I have also strong interest in animal cell culture area, and particularly with shear-sensitive cells as fish and insect cells for its use in human therapeutics, veterinary and agriculture. I possess a large experience with the system baculovirus-insect cell for industrial production of both recombinant proteins and baculovirus as bioinsecticidas using airlift reactors.

At present, I am in the process of building a scientific program involving algae and cell plant culture to meet industry demands and environmental requirements, having already collaborative research on hairy root culture for the production of secondary metabolites.

Subject Area: Disciplines

Research Groups

Future Research

  • Bioremediation: Immobilized cells enzymes for the bioremediation of soil

Publications

  • Pushparajan, C., Claus, J.D. and Visnovsky, G. (2014) Production of Oryctes nudivirus in microcarrier-based insect cell cultures in spinner-flask bioreactors. Wellington, New Zealand: New Zealand Microbological Society Conference 2014, 18-20 Nov 2014. (Conference Contributions - Oral presentations)
  • Pushparajan, C., Claus, J.D. and Visnovsky, G. (2014) Roller bottle technology for the production of Oryctes nudivirus in insect cell cultures. Wellington, New Zealand: New Zealand Microbological Society Conference 2014, 18-20 Nov 2014. (Conference Contributions - Oral presentations)
  • Tejerina, J., Ryan, J., Jeffs, A. and Visnovsky, G. (2014) Screening of bacterial strains with potential applications in biotransforming waste material from New Zealand industries. Wellington, New Zealand: New Zealand Microbiological Society Conference 2014, 18-20 Nov 2014. (Conference Contributions - Poster presentations)
  • Tejerina, J., Ryan, J., Jeffs, A. and Visnovsky, G. (2014) The performance of two bacterial strains in bioprocessing industrial wastes. Wellington, New Zealand: New Zealand Microbiological Society Conference 2014, 18-20 Nov 2014. (Conference Contributions - Poster presentations)
  • Merten, O-W., Bakker, W.A.M., Vorlop, J., Reiter, M., Visnovsky, G., Jäger, V., Merabishvili, M. and Reichl, U. (2014) Virus production under suspension conditions. In Hans-Peter Meyer and Diego Schmidhalter (Ed.), Industrial Scale Suspension Culture of Living Cells (First ed.): 503-554. Weiheim, Germany.: Wiley-VCH Verlag GmbH & Co. (Chapters in Books)
  • Pushparajan, C., Claus, J.D., Marshall, S.D.G. and Visnovsky, G. (2013) Characterization of growth and Oryctes rhinoceros nudivirus production in attached cultures of the DSIR-HA-1179 coleopteran insect cell line. Cytotechnology 65(6): 1003-1016. http://dx.doi.org/10.1007/s10616-013-9632-9. (Journal Articles)
  • Novis, P.M., Smissen, R., Buckley, T., Golapalakrishnan, K. and Visnovsky, G. (2013) Inclusion of Chloroplast that have undergone expansion misleads phylogenetic reconstruction in the Chlorophyta. American Journal of Botany 100(11): 2194-2209. http://www.amjbot.org/cgi/doi/10.3732/ajb.1200584. (Journal Articles)
  • Pushparajan, C., Claus, J.D. and Visnovsky, G. (2012) Development of a process for the large scale production of Oryctes virus in DSIR-HA-1179 insect cell cultures. Nagoya, Japan: 25th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT), 27-30 Nov 2012. In Proceedings: 54. (Conference Contributions - Abstracts)
  • Stelting, S., Burns, R.G., Sunna, A., Visnovsky, G. and Bunt, C.R. (2012) Immobilization of pseudomonas sp. strain ADP: A stable inoculant for the bioremediation of atrazine. Applied Clay Science 64: 90-93. http://dx.doi.org/10.1016/j.clay.2011.12.006. (Journal Articles)
  • Novis, P.M. and Visnovsky, G. (2012) Novel alpine algae from New Zealand: Chlorophyta. Phytotaxa 39: 1-30. (Journal Articles)
  • Gopalakrishnan, K., Visnovsky, G. and Novis, K. (2012) Pigments and lipids from NZ alpine algae. Dunedin, New Zealand: Forum on Algal and Cyanobacterial Biomass, Bioenergy and Bioproducts, 7 Dec 2012. (Conference Contributions - Oral presentations)
  • Claus, J.D., Gioria, V.V., Micheloud, G.A. and Visnovsky, G. (2012) Production of insecticidal baculoviruses in insect cell cultures: Potential and limitations. In S. Soloneski and M. Larramendy (Ed.), Insecticides: Basic and Other Applications: 127-152. Rijeka: INTECH. http://dx.doi.org/10.5772/29551. (Chapters in Books)
  • Visnovsky, G.A., Claus, J.D. and Pushparajan, C. (2012) Towards a feasible process for the large scale production of Oryctes virus in DSIR-HA-1179 insect cell cultures. Buenos Aires, Argentina: 45th Annual Meeting of the Society for Invertebrate Pathology. International Congress on Invertebrate Pathology and Microbial Control, 5-9 Aug 2012. In Program: 79. (Conference Contributions - Abstracts)
  • Ryan, J., Vyssotski, M., Visnovsky, S. and Visnovsky, G. (2011) Eicosapentaenoic acid containing bacteria isolated from New Zealand marine organisms. Hakodate, Japan: Fourth Workshop on Beneficial Marine Lipids as Ingredients for Functional Foods, 7 Oct 2011. (Conference Contributions - Oral presentations)
  • Pushparajan, C., Claus, J.D. and Visnovsky, G. (2011) Evaluation of growth kinetics and susceptibility to infection with Oryctes virus in the DSIR-HA-1179 insect cell line cultivated in different culture media. Chiang Mai, Thailand: 6th International Conference on Biopesticides, 11-16 Dec 2011. In Proceedings of the 6th International Conference on Biopesticides. Chiang Mai, Thailand 178. (Conference Contributions - Poster presentations)
  • Ryan, J.L.J., Vyssotski, M. and Visnovsky, G. (2011) Media optimization of long chain polyunsaturated fatty acid producing marine bacteria. Palmerston North, New Zealand: 56th Annual Scientific Meeting of the New Zealand Microbiological Society (NZSM), 23-25 Nov 2011. (Conference Contributions - Poster presentations)
  • Novis, P.M. and Visnovsky, G. (2011) Novel alpine algae from New Zealand: Cyanobacteria. Phytotaxa 22: 1-24. (Journal Articles)
  • Ryan, J.L.J., Vyssotski, M., Visnovsky, S. and Visnovsky, G. (2011) Occurrence and diversity of EPA producing bacteria isolated from New Zealand fish species. Palmerston North, New Zealand: 56th Annual Scientific Meeting of the New Zealand Microbiological Society (NZMS), 23-25 Nov 2011. (Conference Contributions - Poster presentations)
  • Micheloud, G.A., Gioria, V.V., Eberhardtb, I., Visnovsky, G. and Claus, J. (2011) Production of the Anticarsia gemmatalis multiple nucleopolyhedrovirus in serum-free suspension cultures of the saUFL-AG-286 cell line in stirred reactor and airlift reactor. Journal of Virological Methods 178(1-2): 106-116. http://dx.doi.org/10.1016/j.jviromet.2011.08.024. (Journal Articles)
  • Ryan, J., Farr, H., Visnovsky, S., Vyssotski, M. and Visnovsky, G. (2010) A rapid method for the isolation of eicosapentaenoic acid-producing marine bacteria. Journal of Microbiological Methods 82(1): 49-53. http://dx.doi.org/10.1016/j.mimet.2010.04.001. (Journal Articles)
  • Stelting, S., Burns, R., Sunna, A., Visnovsky, G. and Bunt, C. (2010) Characterization of stabilized formulations of the atrazine degrading bacterium Pseudomonas sp. strain APD. Portland, OR, USA: 37th Annual Meeting & Exposition of the Controlled Release Society (CRS), 10-14 Jul 2010. In Proceedings of the 37th Annual Meeting & Exposition of the Controlled Release Society (CRS) 2pp. (Conference Contributions - Papers in published proceedings)
  • Ryan, J., Visnovsky, G., Farr, H., Visnovsky, S. and Vyssotski, M. (2010) Eicosapentaenoic acid containing bacteria isolated from New Zealand marine organisms. Tokyo, Japan: First Workshop on Beneficial Marine Lipids as Ingredients for Functional Foods, 26 Apr 2010. In Proceedings 22-23. (Conference Contributions - Abstracts)
  • Pushparajan, C., Claus, J.D., Gioria, V.V. and Visnovsky, G. (2010) Evaluation of growth and metabolism of the DSIR-HA-1179 insect cell line in a low cost-serum free culture medium. Univerrsity of Canterbury, Christchurch, New Zealand: SCENZ-IChemE 2010 Conference and AGM, 4 Sep 2010. (Conference Contributions - Poster presentations)
  • Pushparajan, C., Claus, J.D., Gioria, V.V. and Visnovsky, G. (2010) Evaluation of growth and metabolism of the DSIR-HA-1179 insect cell line in a low cost-serum free culture medium. University of Canterbury, Christchurch, New Zealand: UC Showcase Postgraduate Research Conference, 2 Sep 2010. In Proceedings of the UC Showcase Postgraduate Research Conference 2. (Conference Contributions - Abstracts)
  • Stelting, S., Burns, R., Sunna, A., Visnovsky, G. and Bunt, C. (2010) Immobilisation of Pseudomonas sp. strain ADP: an approach for bioremediation of herbicides. Dunedin, New Zealand: Microbial Products: Exploiting Microbial Diversity for Sustainable Plant Production, 10 Aug 2010. In Proceedings 97-102. (Conference Contributions - Papers in published proceedings)
  • Stelting, S., Burns, R., Sunna, A., Visnovsky, G. and Bunt, C. (2010) Immobilization of Pseudomonas sp. strain ADP: a stable inoculant for the bioremediation of atrazine. Brisbane, Australia: 19th World Congress of Soil Science, 1-6 Aug 2010. In Proceedings of the 19th World Congress of Soil Science 4pp. (Conference Contributions - Papers in published proceedings)
  • Peled, A., Merchuk, J., Visnovsky, G. and Enden, G. (2010) Insect cells-baculovirus infection dynamics mathematical modelling. Beer-Sheva, Israel: Final year project poster exhibition, Department of Biomedical Engineering, Ben-Gurion University, Beer-Sheva, Israel, 14 Jun 2010. (Conference Contributions - Poster presentations)
  • Stelting, S., Visnovsky, G. and Bunt, C. (2009) A room temperature stable Pseudomonas ADP formulation for bioremediation. Hobart, Australia: Australasian Pharmaceutical Sciences Association Annual Conference, 9-11 Dec 2009. In Proceedings of the Australasian Pharmaceutical Sciences Association Annual Conference 104. (Conference Contributions - Abstracts)
  • Stelting, S., Burns, R., Sunna, A., Visnovsky, G. and Bunt, C. (2009) Bioremediation of herbicides. Dunedin, New Zealand: Microbial Products: Exploiting Microbial Diversity for Sustainable Plant Production, 10 Aug 2009. (Conference Contributions - Abstracts)
  • Ryan, J., Farr, H., Zhu, Y., Vyssotski, M. and Visnovsky, G. (2009) Development of a rapid screening method for long chain polyunsaturated fatty acid producing marine bacteria. Sydney, Australia: World Congress on Fats and Oils and 28th ISF Congress, 27-30 Sep 2009. (Conference Contributions - Oral presentations)
  • Visnovsky, G., O'Callaghan, M. and Jackson, T. (2009) Estudios primarios para la producción en gran escala del agente de control biológico Pseudomonas fluorescens 113. Chillán, Chile: Segundo Simposio Chileno de Control Biológico, 12-15 May 2009. In Proceedings of Segundo Simposio Chileno de Control Biológico 72. (Conference Contributions - Abstracts)
  • Novis, P. and Visnovsky, G. (2008) A culture collection of alpine algae at the Allan Herbarium, Landcare. Phycology and Engineering: A meeting of two worlds? Wellington, New Zealand: 5th Asia Pacific Phycological Forum (Vth APPA), 10-14 Nov 2008. (Conference Contributions - Poster presentations)
  • Visnovsky, G.A., Smalley, D.J., O'Callaghan, M. and Jackson, T.A. (2008) Influence of culture medium composition, dissolved oxygen concentration and harvesting time on the production of Serratia entomophila, a microbial control agent of the New Zealand grass grub. Biocontrol Science and Technology 18(1): 87-100. http://dx.doi.org/10.1080/09583150701760513. (Journal Articles)
  • Visnovsky, G., Merchuk, J. and Claus, J.D. (2008) Influence of Dissolved Oxygen Concentration on saUFL-AG-286 Cells Growth and Polyhedral Inclusion Bodies Kinetics Production. Córdoba, Argentina: XLIV Annual Meeting of the Society for Research in Argentina Biochemistry and Molecular Biology, 8-11 Nov 2008. In BIOCELL 32 (Supplement) 55. (Conference Contributions - Poster presentations)
  • Visnovsky, G., Swaminathan, J. and Jackson, T. (2008) Towards a feasible process for industrial manufacture of Pantoea agglomerans: Preliminary studies on fermentation and formulation processes (in Spanish). La Estanzuela, Colonia, Uruguay: Segundo Taller Uruguayo de Agentes Microbianos de Control Biologico, 4-5 Sep 2008. In Proceedings of Segundo Taller Uruguayo de Agentes Microbianos de Control Biologico 19-20. (Conference Contributions - Papers in published proceedings)
  • Visnovsky, G. and Alzugaray, R. (2007) Producción de entomopatógenos como objetivo estratégico del control de plagas. Brasilia, Brazil: Biological Control: from Mass Production to Commercialization. X SICONBIOL Simpósio IOBC/SRNT- Simpósio da IOBC/Seção Regional Neotropical, 30 Jun-4 Jul 2007. (Conference Contributions - Oral presentations)
  • Alzugaray, R. and Visnovsky, G. (Ed.) (2006) Proceedings of the First Uruguayan Workshop on Bioproduction of Biological Control Agents. Montevideo: Instituto Nacional de Investigaciones Agropecuarias, INIA. 72pp. (Edited Books)
  • Visnovsky, G. (2006) Process optimization for large-scale production of Serratia entomophila. Colonia, Uruguay: First Uruguayan Workshop on Bioproduction of Biological Control Agents, 21-22 Mar 2006. In Proceedings of the First Uruguayan Workshop on Bioproduction of Biological Control Agents 45-46. (Conference Contributions - Papers in published proceedings)
  • Visnovsky, G. (2005) Baculovirus mass production. Lincoln, New Zealand: First German/New Zealand Workshop on Microbial Bioproduction, 21-23 Mar 2005. In Proceeding of the First German/New Zealand Workshop on Microbial Bioproduction 57-58. (Conference Contributions - Papers in published proceedings)
  • Visnovsky, G. (2005) High cell density production of Serratia entomophila. Lincoln, New Zealand: First German/New Zealand Workshop on Microbial Bioproduction, 21-23 Mar 2005. In Proceeding of the First German/New Zealand Workshop on Microbial Bioproduction 35-36. (Conference Contributions - Papers in published proceedings)
  • Visnovsky, G. (2005) Large-scale production of Serratia entomophila. Cordoba, Argentina: 44th Annual Meeting- Argentine Society for Biochemistry and Molecular Biology research, Dec 2005. In BIOCELL 97. (Conference Contributions - Abstracts)
  • Visnovsky, G. and Merchuk, J.C. (2004) Optimization of a process for the production of baculovirus in large scale bioreactors. Prague, Czech Republic: 16th International Congress of Chemical and Process Engineering, 22-26 Aug 2004. (Conference Contributions - Oral presentations)
  • Visnovsky, G., Claus, J. and Merchuk, J.C. (2003) Airlift reactors as a tool for insect cells and baculovirus mass production. Latin-America Applied Research 33: 117-121. (Journal Articles)
  • Visnovsky, G. and Merchuk, J.C. (2003) Influence of dissolved oxygen concentration on the UFL-Ag-286 insect cell growth and polyhedra production: a preliminary study. Rehovot, Israel: Fourth Annual Conference on Active Research by Environmental Sciences Students, CARESS 2003, 11 Jun 2003. In Proccedings of the Fourth Annual Conference on Active Research by Environmental Sciences Students, CARESS 2003 39. (Conference Contributions - Poster presentations)
  • Visnovsky, G. and Merchuk, J.C. (2003) Kinetics Production of AgMNPV in Optimized Airlift Reactor. Rehovot, Israel: Fourth Annual Conference on Active Research by Environmental Sciences Students, CARESS 2003, 11 Jun 2003. In Proceeding of the Fourth Annual Conference on Active Research by Environmental Sciences Students, CARESS 2003 34. (Conference Contributions - Poster presentations)
  • Zang Y.H., Visnovsky., G., Merchuk. and J.C. (2003) Poly-peaks dynamic phenomena in infection process at low multiplicity of infection. Thessaloniki, Greece: 3rd Chemical Engineering Conference for Collaborative Research in Eastern Mediterranean, 15-17 May 2003. 4pp. (Conference Contributions - Full conference papers)
  • Visnovsky, G., Claus, J. and Merchuk, J.C. (2002) Culture of insect cells in airlift reactors: study of the influence of geometrical characteristics and gas flow rate on culture behaviour. Iguassu Falls, Brazil: XXXVth Annual Meeting of the Society of Invertebrate Pathology Culture, 17-23 Aug 2002. 60-61. (Conference Contributions - Poster presentations)
  • Visnovsky, G. (2002) Membranes: its use in the industry and biotechnology. Beer Sheva: Ben Gurion University of the Negev. 35pp. (Monographs)
  • Visnovsky, G., Claus, J. and Merchuk, J.C. (2002) Study of the production of Anticarsia gemmatalis nucleopolyhedrovirus in airlift reactors of different geometrical design. Iguassu Falls, Brazil: XXXVth Annual Meeting of the Society of Invertebrate Pathology Culture, 17-23 Aug 2002. (Conference Contributions - Poster presentations)
  • Visnovsky, G., Claus, J. and Merchuk, J.C. (2001) Airlift Reactors as a Tool for Insect Cells and Baculovirus Mass Production. Madrid, Spain: 10th European Congress of Biotechnology, ECB10, 8-11 Jul. 118. (Conference Contributions - Poster presentations)
  • Visnovsky, G., Merchuk, J.C., Leguizamon E., Claus. and J. (2001) Evaluation of a homologous cell line to develop a process to produce Anticarsia gemmatalis multiple nuclear polyhedrosis virus in vitro.. Rehovot, Israel: Third Annual Conference on Active Research by Environmental Sciences Students, CARESS 2001, 14 Jun 2001. In Proceedings of the Third Annual Conference on Active Research by Environmental Sciences Students, CARESS 2001 26. (Conference Contributions - Poster presentations)
  • Visnovsky, G., Claus, J. and Merchuk, J.C. (2001) Growth of Spodoptera frugiperda Insect Cells in Airlift Reactors of Different Configuration. Beer-Sheva, Israel: Annual Meeting of the Israel Society for Microbiology (ISM), 26-27 Feb 2001. (Conference Contributions - Poster presentations)
  • Visnovsky, G. (2001) Is it possible to combine wind and solar energy? Beer-Sheva: Ben-Gurion University of the Negev, Israel. 26pp. (Monographs)
  • Visnovsky, G., Claus, J. and Merchuk, J.C. (2001) Optimization of the culture of insect cells for the production of viral-based pesticides in airlift reactors: influence of geometrical design and superficial gas velocity. Santa Fe, Argentina: 3rd MercoSur Congress on Process Systems Engineering and 1st MercorSur Congress on Chemical Engineering, ENPROMER, 16-20 Sep 2002. In Proceeding of the 3rd MercoSur Congress on Process Systems Engineering and 1st MercorSur Congress on Chemical Engineering, ENPROMER 1837-1842. (Conference Contributions - Full conference papers)
  • Visnovsky, G., Claus, J. and Merchuk, J.C. (2001) The use of concentric-tube airlift reactors for growth of insect cells. Ankara, Turkey: Chemical Engineering Conference for Collaborative Research in Eastern Mediterranean. Middle East Technical University, 20-24 May 2001. 20. (Conference Contributions - Abstracts)
  • Visnovsky, G., Sabtai, I. and Merchuk, J.C. (2000) Importance of Geometrical Design on Performance of Airlift Reactors in the Production of Viral-Based Pesticides. Beer-Sheva, Israel: Annual Meeting of the Israel Society for Microbiology (ISM)., 25-26 Jun 2000. 40. (Conference Contributions - Poster presentations)
  • Visnovsky, G., Shabtai, I. and Merchuk, J.C. (2000) Production of Viral Insecticides: Importance of Geometrical Design on Performance of Airlift Reactors. Haifa, Israel: XXX Annual Meeting of the Israel Society for Ecology and Environmental, 19-20 Jun 2000. 178. (Conference Contributions - Poster presentations)
  • Visnovsky, G., Shabtai, I. and Merchuk, J.C. (2000) Study of the Influence of Pluronic F-68 and Silicon Antifoam on the Growth of Insect Cell Cultures. Mendoza, Argentina: XXXV Annual Meeting of the Argentine Society of Investigation in Biochemistry and Molecular Biology, SAIB ’99, 26-29 Nov 1999. (Conference Contributions - Poster presentations)
  • Merchuk, J.C., Visnovsky, G., Gluz, M. and Mukmenev, I. (2000) The Use of Helical Flow Promoters for Shear Sensitive cultures. Beer-Sheva, Israel: Annual Meeting of the Chemical Engineering Society of Israel (ISM), 25-26 June 2000. 42. (Conference Contributions - Poster presentations)
  • Merchuk, J., C., Nakahara., T., Visnovsky., G., Gluz., M., Mukmenev. and I. (2000) The use of helical flow promoters for shear sensitive cultures. Dresden, Germany: 5th German-Japanese Symposium of Bubble Columns, 2002. In Proceeding of the 5th German-Japanese Symposium of Bubble Columns 85-92. (Conference Contributions - Full conference papers)
  • Visnovsky, G., Shabtai, I. and Merchuk, J.C. (1999) Biological insecticides: Modeling, optimization and experimental study of the replication of Anticarsia gemmatalis nuclear polyhedrosis virus in insect cell cultures grown in airlift reactors with helical flow promoters. Rehovot, Israel: Annual Meeting of the Israel Society for Microbiology (ISM), Weizmann Institute of Science, 28 Feb - Mar 3, 1999. (Conference Contributions - Poster presentations)
  • Visnovsky, G., Shabtai, I. and Merchuk, J. (1999) Influence of silicone antifoam and pluronic F-68 on insect cells culture growing in airlift reactors. Rehovot, Israel: Second Annual Conference on Active Research by Environmental Sciences Students, CARESS ‘99. Weizmann Institute of Science, 29 May 1999. 14. (Conference Contributions - Poster presentations)
  • Visnovsky, G., Shabtai, I. and Merchuk, J.C. (1999) Optimization of Lepidopteran Cell Culture in Airlift Reactors: Influence of Glucose Concentration and Inlet Flow Rate. Mendoza, Argentina: XXXV Annual Meeting of the Argentine Society of Investigation in Biochemistry and Molecular Biology, SAIB ’99, 26-29 Nov 1999. (Conference Contributions - Poster presentations)
  • Visnovsky, G., Shabtai, I. and Merchuk, J.C. (1999) Use of baculovirus as agent control pest: optimization of virus production in airlift reactors. Jerusalem, Israel: The 7th International Conference of the Israel Society for Ecology and Environmental Quality Sciences on Environmental Challenges for the next Millennium, 13-18 June 1999. In Proceeding of the 7th International Conference of the Israel Society for Ecology and Environmental Quality Sciences on Environmental Challenges for the next Millennium 130. (Conference Contributions - Poster presentations)
  • Visnovsky, G. (1998) Ginseng…the magic plant: production of gingenosides from plant cell culture of Panax ginseng. Beer-Sheva: Ben-Gurion University of the Negev, Israel. 29pp. (Monographs)
  • Visnovsky, G., Shabtai, I. and Merchuk, J.C. (1998) Modeling, optimization and experimental study of the replication of Anticarsia gemmatalis nuclear polyhedrosis virus in insect cell cultures grown in airlift reactors with helical flow promoters. Beer-Sheva, Israel: Environment Quality Journeys. The Institutes for Applied Research, Ben-Gurion University of the Negev, October 12, 1998. In Proceedings of the Environment Quality Journeys. The Institutes for Applied Research, Ben-Gurion University of the Negev 44. (Conference Contributions - Poster presentations)
  • Didier, C., Visnovsky, G. and Claus, J. (1997) Optimization of a simple process for the production of polyhedron of Anticarsia gemmatalis nuclear polyhedrosis virus in batch cultures of the cell line IPLB-Sf-21 supplemented with foetal bovine serum. Cordoba, Argentina: XXXIII Annual Meeting Argentine Society for the Investigating in Biochemistry and Molecular Biology, Nov 1997. (Conference Contributions - Abstracts)
  • Claus, J. and Visnovsky, G. (1996) Influence of cultural factors on the multiplication of Anticarsia gemmatalis nuclear polyhedrosis virus in insect cell cultures. Tandil, Argentina: V Argentine Congress of Virology and II Meeting of Latin-American Virology, April, 1996. (Conference Contributions - Oral presentations)
  • Claus, J., Didier, C. and Visnovsky, G. (1996) Origin of the limitation in the replication of Anticarsia gemmatalis nuclear polyhedrosis virus in cultures of stationary phase. Tandil, Argentina: V Argentine Congress of Virology and II Meeting of Latin-American Virology, Apr 2006. (Conference Contributions - Oral presentations)
  • Visnovsky, G. and Claus, J. (1995) Comparation of different strategies to produce the Anticarsia gemmatalis nuclear polyhedrosis virus in insect cell cultures. Santa Fe, Argentina: Ibero-American Journeys of Bioprocesses, 11-12 Oct 1995. (Conference Contributions - Oral presentations)
  • Visnovsky, G. and Claus, J. (1994) Influence of the time and multiplicity of infection on the batch production of Anticarsia gemmatalis nuclear polyhedrosis virus in lepidopteran insect cell cultures. Advances in Bioprocess Engineering : 123-128. (Journal Articles)
  • Visnovsky, G. (1994) Production of a biopesticide into a last generation reactor: parameters optimization. Santa Fe: Facultad de Bioquimica y Ciencias Biologicas, Universidad Nacional del Litoral, Santa Fe, Argentina. 37pp. (Monographs)
  • Visnovsky, G. and Claus, J. (1994) Study of the influence of the infection parameters on the production of Anticarsia gemmatalis nuclear polyhedrosis virus in lepidopteran insect cell cultures. Salto, Uruguay: Seconds Investigations Journeys of the Montevideo Group for Young Investigators, 21-23 Sep 1994. (Conference Contributions - Oral presentations)
  • Visnovsky, G. and Claus, J. (1993) Optimization of the variables of infection for the production of baculovirus in cell cultures. Santiago, Chile: III Latin-American Congress of Biotechnology, 16-19 Nov 1994. (Conference Contributions - Oral presentations)
  • Visnovsky, G. and Claus, J. (1993) Production in vitro of the nuclear polyhedrosis virus of Anticarsia gemmatalis, biological control agent of the velvetbean caterpillar.. Santa Fe, Argentina: 2nd Scientific and Technologic Journeys, Secretary of Science and Technology, National University of Litoral, Santa Fe, Argentina, 1993. In Proceeding of the 2nd Scientific and Technologic Journeys 23. (Conference Contributions - Abstracts)
  • Visnovsky, G. and Claus, J. (1993) Production of Anticarsia gemmatalis nuclear polyhedrosis virus in lepidopteran insect cell cultures: effect of the cellular density. Tucuman, Argentina: IV Argentine Congress of Virology, 5-8 Sep 1993. (Conference Contributions - Poster presentations)
  • Visnovsky, G. and Claus, J. (1992) Multiplication in cell cultures of an isolation of the Anticarsia gemmatalis nuclear polyhedrosis virus.. Buenos Aires, Argentina: XIV Annual Scientific Meeting of the Argentine Society of Virology, 10-11 Dec 1992. (Conference Contributions - Oral presentations)