UC SPARK - University of Canterbury - New Zealand

Dr Gabriel Alberto Visnovsky

Chemical and Process Engineering

Fields of Research

  • Biotechnology
  • Biochemical engineering
  • Bioprocess engineering and optimisation
  • Fermentation and bioreactor design
  • Insect cell culture and baculovirus expression vector system
  • High cell density cultures of animal cells and microorganisms
  • Algae, cell plant and hairy root culture
  • Environmental biotechnology

Researcher Summary

My current research is focussed in the development of industrial processes for the production of large-scale, high cell density cultures of bacteria and fungi for their use as biological control agents or for their valuable secondary metabolites. An important part of this research is in understanding and manipulating the variables that play a key role in the production process, the relationships between them and how these influence on the whole process. Examples of these variables are: strain selection, culture medium development, optimisation of the fermentation conditions, bioreactor selection, design and operation, fermentation strategy, bioprocess stoichiometry and bioprocess design.

I have also strong interest in animal cell culture area, and particularly with shear-sensitive cells as fish and insect cells for its use in human therapeutics, veterinary and agriculture. I possess a large experience with the system baculovirus-insect cell for industrial production of both recombinant proteins and baculovirus as bioinsecticidas using airlift reactors.

At present, I am in the process of building a scientific program involving algae and cell plant culture to meet industry demands and environmental requirements, having already collaborative research on hairy root culture for the production of secondary metabolites.

Subject Area: Disciplines

Research Groups

Future Research

  • Bioremediation: Immobilized cells enzymes for the bioremediation of soil

Research/Scholarly/Creative Works

Authored Book
  • Visnovsky G. (2002) Membranes: its use in the industry and biotechnology. Beer-Sheva: Ben Gurion University of the Negev. 35pp.
  • Visnovsky G. (2001) Is it possible to combine wind and solar energy? Beer-Sheva: Ben-Gurion University of the Negev, Israel. 26pp.
  • Visnovsky G. (1998) Ginseng…the magic plant: production of gingenosides from plant cell culture of Panax ginseng. Beer-Sheva: Ben-Gurion University of the Negev, Israel. 29pp.
  • Visnovsky G. (1994) Production of a biopesticide into a last generation reactor: parameters optimization. Santa Fe: Facultad de Bioquimica y Ciencias Biologicas, Universidad Nacional del Litoral, Santa Fe, Argentina. 37pp.
Journal Article
  • Visnovsky GA., Pushparajan CH., Claus JD. and Marshall SDG. (2017) Nutritional demands and metabolic characteristics of the DSIR-HA-1179 insect cell line during growth and infection with the Oryctes nudivirus. Journal of tissue culture methods : Tissue Culture Association manual of cell, tissue, and organ culture procedures (Submitted)
  • Moore SL., Berthomier L., Braganza CD., MacKichan JK., Ryan JL., Visnovsky G. and Keyzers RA. (2016) Identification, library synthesis and anti-vibriosis activity of 2-benzyl-4-chlorophenol from cultures of the marine bacterium Shewanella halifaxensis. Bioorganic and Medicinal Chemistry Letters 26(13): 3086-3088. http://dx.doi.org/10.1016/j.bmcl.2016.05.002.
  • Quintana S., Brasesco C., Negri P., Marin M., Visnovsky G., Pagnuco I., Medici S., Szawarski Varsani A., Ruffinengo S. and Eguaras Maggi M. (2016) Differential immunogene expression of the honey bee Apis mellifera associated with deformed wing virus infection in Argentina. Journal of Invertebrate Pathology (Submitted)
  • Novis PM., Smissen R., Buckley T., Golapalakrishnan K. and Visnovsky G. (2013) Inclusion of Chloroplast that have undergone expansion misleads phylogenetic reconstruction in the Chlorophyta. American Journal of Botany 100(11): 2194-2209. | http://www.amjbot.org/cgi/doi/10.3732/ajb.1200584.
  • Pushparajan C., Claus JD., Marshall SDG. and Visnovsky G. (2013) Characterization of growth and Oryctes rhinoceros nudivirus production in attached cultures of the DSIR-HA-1179 coleopteran insect cell line. Cytotechnology 65(6): 1003-1016. http://dx.doi.org/10.1007/s10616-013-9632-9.
  • Novis PM. and Visnovsky G. (2012) Novel alpine algae from New Zealand: Chlorophyta. Phytotaxa 39: 1-30.
  • Stelting S., Burns RG., Sunna A., Visnovsky G. and Bunt CR. (2012) Immobilization of pseudomonas sp. strain ADP: A stable inoculant for the bioremediation of atrazine. Applied Clay Science 64: 90-93. http://dx.doi.org/10.1016/j.clay.2011.12.006.
  • Micheloud GA., Gioria VV., Eberhardtb I., Visnovsky G. and Claus J. (2011) Production of the Anticarsia gemmatalis multiple nucleopolyhedrovirus in serum-free suspension cultures of the saUFL-AG-286 cell line in stirred reactor and airlift reactorProduction of the Anticarsia gemmatalis multiple nucleopolyhedrovirus in serum-free suspension cultures of the saUFL-AG-286 cell line in stirred reactor and airlift reactorProduction of the Anticarsia gemmatalis multiple nucleopolyhedrovirus in serum-free suspension cultures of the saUFL-AG-286 cell line in stirred reactor and airlift reactorProduction of the Anticarsia gemmatalis multiple nucleopolyhedrovirus in serum-free suspension cultures of the saUFL-AG-286 cell line in stirred reactor and airlift reactorProduction of the Anticarsia gemmatalis multiple nucleopolyhedrovirus in serum-free suspension cultures of the saUFL-AG-286 cell line in stirred reactor and airlift reactorProduction of the Anticarsia gemmatalis multiple nucleopolyhedrovirus in serum-free suspension cultures of the saUFL-AG-286 cell line in stirred reactor and airlift. Journal of Virological Methods 178(1-2): 106-116. http://dx.doi.org/10.1016/j.jviromet.2011.08.024.
  • Novis PM. and Visnovsky G. (2011) Novel alpine algae from New Zealand: Cyanobacteria. Phytotaxa 22: 1-24.
  • Ryan J., Farr H., Visnovsky S., Vyssotski M. and Visnovsky G. (2010) A rapid method for the isolation of eicosapentaenoic acid-producing marine bacteria. Journal of Microbiological Methods 82(1): 49-53. http://dx.doi.org/10.1016/j.mimet.2010.04.001.
  • Visnovsky GA., Smalley DJ., O'Callaghan M. and Jackson TA. (2008) Influence of culture medium composition, dissolved oxygen concentration and harvesting time on the production of Serratia entomophila, a microbial control agent of the New Zealand grass grub. Biocontrol Science and Technology 18(1): 87-100. http://dx.doi.org/10.1080/09583150701760513.
  • Visnovsky G., Claus J. and Merchuk JC. (2003) Airlift reactors as a tool for insect cells and baculovirus mass production. Latin-America Applied Research 33: 117-121.
  • Visnovsky G., Claus JD. and Merchuk JC. (2003) Cultivation of insect cells in airlift reactors: Influence of reactor configuration and superficial gas velocity. Latin American Applied Research 33(3): 207-211.
  • Visnovsky G. and Claus J. (1994) Influence of the time and multiplicity of infection on the batch production of Anticarsia gemmatalis nuclear polyhedrosis virus in lepidopteran insect cell cultures. Advances in Bioprocess Engineering : 123-128.
Edited Volume
  • Alzugaray R. and Visnovsky G. (Ed.) (2006) Proceedings of the First Uruguayan Workshop on Bioproduction of Biological Control Agents. Montevideo: Instituto Nacional de Investigaciones Agropecuarias, INIA. 72pp.
Chapter
  • Reid S., Chan LCL., Matindoost L., Pushparajan C. and Visnovsky G. (2015) Cell culture for production of insecticidal viruses. In Glare T; Moran-Diez M (Ed.), Microbial-Based Biopesticides, Methods & Protocols New York: Springer.
  • Merten OW., Bakker WAM., Vorlop J., Reiter M., Visnovsky G., Jäger V., Merabishvili M. and Reichl U. (2014) Virus production under suspension conditions. In Meyer HP; Schmidhalter D (Ed.), Industrial Scale Suspension Culture of Living Cells: 503-554. Weiheim: Wiley-VCH Verlag GmbH & Co.
  • Claus JD., Gioria VV., Micheloud GA. and Visnovsky G. (2012) Production of insecticidal baculoviruses in insect cell cultures: Potential and limitations. In Soloneski S; Larramendy M (Ed.), Insecticides: Basic and Other Applications: 127-152. Rijeka: INTECH. http://dx.doi.org/10.5772/29551.
Conference Contribution - Published
  • Stelting S., Burns R., Sunna A., Visnovsky G. and Bunt C. (2010) Characterization of stabilized formulations of the atrazine degrading bacterium Pseudomonas sp. strain APD. Portland, OR, USA: 37th Annual Meeting & Exposition of the Controlled Release Society (CRS), 10-14 Jul 2010. In Proceedings of the 37th Annual Meeting & Exposition of the Controlled Release Society (CRS): 2pp.
  • Stelting S., Burns R., Sunna A., Visnovsky G. and Bunt C. (2010) Immobilisation of Pseudomonas sp. strain ADP: an approach for bioremediation of herbicides. Dunedin, New Zealand: Microbial Products: Exploiting Microbial Diversity for Sustainable Plant Production, 10-10 Aug 2010. In Proceedings: 97-102.
  • Stelting S., Burns R., Sunna A., Visnovsky G. and Bunt C. (2010) Immobilization of Pseudomonas sp. strain ADP: a stable inoculant for the bioremediation of atrazine. Brisbane, Australia: 19th World Congress of Soil Science, 1-6 Aug 2010. In Proceedings of the 19th World Congress of Soil Science: 4pp.
  • Visnovsky G., Swaminathan J. and Jackson T. (2008) Towards a feasible process for industrial manufacture of Pantoea agglomerans: Preliminary studies on fermentation and formulation processes (in Spanish). La Estanzuela, Colonia, Uruguay: Segundo Taller Uruguayo de Agentes Microbianos de Control Biologico, 4-5 Sep 2008. In Proceedings of Segundo Taller Uruguayo de Agentes Microbianos de Control Biologico: 19-20.
  • Visnovsky G. (2006) Process optimization for large-scale production of Serratia entomophila. Colonia, Uruguay: First Uruguayan Workshop on Bioproduction of Biological Control Agents, 21-22 Mar 2006. In Proceedings of the First Uruguayan Workshop on Bioproduction of Biological Control Agents: 45-46.
  • Visnovsky G. (2005) Baculovirus mass production. Lincoln, New Zealand: First German/New Zealand Workshop on Microbial Bioproduction, 21 Mar 2005. In Proceeding of the First German/New Zealand Workshop on Microbial Bioproduction: 57-58.
  • Visnovsky G. (2005) High cell density production of Serratia entomophila. Lincoln, New Zealand: First German/New Zealand Workshop on Microbial Bioproduction, 21 Mar 2005. In Proceeding of the First German/New Zealand Workshop on Microbial Bioproduction: 35-36.
Conference Contribution - Other
  • Visnovsky GA., Pushparajan CH. and Claus JD. (2017) A microcarrier-based process for production of the Oryctes nudivirus in spinner-flask bioreactors.. San Diego, California, United States of America: 50th Annual Meeting for Invertebrate Pathology, 13-17 Aug 2017
  • Visnovsky G., Pushparajan C., Marshal SDG. and Claus JD. (2015) Production of Oryctes nudivirus in DSIR-HA-1179 insect cell cultures in roller bottle systems. Vancouver, Canada: International Congress on Invertebrate Pathology and Microbial Control and the 48th Annual Meeting for Invertebrate Pathology, 9-13 Aug 2015
  • Pushparajan C., Claus JD. and Visnovsky G. (2014) Production of Oryctes nudivirus in microcarrier-based insect cell cultures in spinner-flask bioreactors. Wellington, New Zealand: New Zealand Microbological Society Conference 2014, 18-20 Nov 2014
  • Pushparajan C., Claus JD. and Visnovsky G. (2014) Roller bottle technology for the production of Oryctes nudivirus in insect cell cultures. Wellington, New Zealand: New Zealand Microbological Society Conference 2014, 18-20 Nov 2014
  • Tejerina J., Ryan J., Jeffs A. and Visnovsky G. (2014) Screening of bacterial strains with potential applications in biotransforming waste material from New Zealand industries. Wellington, New Zealand: New Zealand Microbiological Society Conference 2014, 18-20 Nov 2014
  • Tejerina J., Ryan J., Jeffs A. and Visnovsky G. (2014) The performance of two bacterial strains in bioprocessing industrial wastes. Wellington, New Zealand: New Zealand Microbiological Society Conference 2014, 18-20 Nov 2014
  • Gopalakrishnan K., Visnovsky G. and Novis K. (2012) Pigments and lipids from NZ alpine algae. Dunedin, New Zealand: Forum on Algal and Cyanobacterial Biomass, Bioenergy and Bioproducts, 7-7 Dec 2012
  • Pushparajan C., Claus JD. and Visnovsky G. (2012) Development of a process for the large scale production of Oryctes virus in DSIR-HA-1179 insect cell cultures. Nagoya, Japan: 25th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT), 27-30 Nov 2012
  • Visnovsky GA., Claus JD. and Pushparajan C. (2012) Towards a feasible process for the large scale production of Oryctes virus in DSIR-HA-1179 insect cell cultures. Buenos Aires, Argentina: 45th Annual Meeting of the Society for Invertebrate Pathology. International Congress on Invertebrate Pathology and Microbial Control, 5-9 Aug 2012
  • Pushparajan C., Claus JD. and Visnovsky G. (2011) Evaluation of growth kinetics and susceptibility to infection with Oryctes virus in the DSIR-HA-1179 insect cell line cultivated in different culture media. Chiang Mai, Thailand: 6th International Conference on Biopesticides, 11-16 Dec 2011
  • Ryan J., Vyssotski M., Visnovsky S. and Visnovsky G. (2011) Eicosapentaenoic acid containing bacteria isolated from New Zealand marine organisms. Hakodate, Japan: Fourth Workshop on Beneficial Marine Lipids as Ingredients for Functional Foods, 7-7 Oct 2011
  • Ryan JLJ., Vyssotski M. and Visnovsky G. (2011) Media optimization of long chain polyunsaturated fatty acid producing marine bacteria. Palmerston North, New Zealand: 56th Annual Scientific Meeting of the New Zealand Microbiological Society (NZSM), 23-25 Nov 2011
  • Ryan JLJ., Vyssotski M., Visnovsky S. and Visnovsky G. (2011) Occurrence and diversity of EPA producing bacteria isolated from New Zealand fish species. Palmerston North, New Zealand: 56th Annual Scientific Meeting of the New Zealand Microbiological Society (NZMS), 23-25 Nov 2011
  • Peled A., Merchuk J., Visnovsky G. and Enden G. (2010) Insect cells-baculovirus infection dynamics mathematical modelling. Beer-Sheva, Israel: Final year project poster exhibition, Department of Biomedical Engineering, Ben-Gurion University, Beer-Sheva, Israel, 14-14 Jun 2010
  • Pushparajan C., Claus JD., Gioria VV. and Visnovsky G. (2010) Evaluation of growth and metabolism of the DSIR-HA-1179 insect cell line in a low cost-serum free culture medium. Univerrsity of Canterbury, Christchurch, New Zealand: SCENZ-IChemE 2010 Conference and AGM, 4-4 Sep 2010
  • Pushparajan C., Claus JD., Gioria VV. and Visnovsky G. (2010) Evaluation of growth and metabolism of the DSIR-HA-1179 insect cell line in a low cost-serum free culture medium. University of Canterbury, Christchurch, New Zealand: UC Showcase Postgraduate Research Conference, 2-2 Sep 2010
  • Ryan J., Visnovsky G., Farr H., Visnovsky S. and Vyssotski M. (2010) Eicosapentaenoic acid containing bacteria isolated from New Zealand marine organisms. Tokyo, Japan: First Workshop on Beneficial Marine Lipids as Ingredients for Functional Foods, 26-26 Apr 2010
  • Ryan J., Farr H., Zhu Y., Vyssotski M. and Visnovsky G. (2009) Development of a rapid screening method for long chain polyunsaturated fatty acid producing marine bacteria. Sydney, Australia: World Congress on Fats and Oils and 28th ISF Congress, 27-30 Sep 2009
  • Stelting S., Burns R., Sunna A., Visnovsky G. and Bunt C. (2009) Bioremediation of herbicides. Dunedin, New Zealand: Microbial Products: Exploiting Microbial Diversity for Sustainable Plant Production, 10-10 Aug 2009
  • Stelting S., Visnovsky G. and Bunt C. (2009) A room temperature stable Pseudomonas ADP formulation for bioremediation. Hobart, Australia: Australasian Pharmaceutical Sciences Association Annual Conference, 9-11 Dec 2009
  • Visnovsky G., O'Callaghan M. and Jackson T. (2009) Estudios primarios para la producción en gran escala del agente de control biológico Pseudomonas fluorescens 113. Chillán, Chile: Segundo Simposio Chileno de Control Biológico, 12-15 May 2009
  • Novis P. and Visnovsky G. (2008) A culture collection of alpine algae at the Allan Herbarium, Landcare. Phycology and Engineering: A meeting of two worlds? Wellington, New Zealand: 5th Asia Pacific Phycological Forum (Vth APPA), 10-14 Nov 2008
  • Visnovsky G., Merchuk J. and Claus JD. (2008) Influence of Dissolved Oxygen Concentration on saUFL-AG-286 Cells Growth and Polyhedral Inclusion Bodies Kinetics Production. Córdoba, Argentina: XLIV Annual Meeting of the Society for Research in Argentina Biochemistry and Molecular Biology, 8-11 Nov 2008
  • Visnovsky G. and Alzugaray R. (2007) Producción de entomopatógenos como objetivo estratégico del control de plagas. Brasilia, Brazil: Biological Control: from Mass Production to Commercialization. X SICONBIOL Simpósio IOBC/SRNT- Simpósio da IOBC/Seção Regional Neotropical, 30 Jun-4 Jul 2007
  • Visnovsky G. (2005) A successful process for the production of a biological control agent in New Zealand. Christchurch, New Zealand: Zealand Royal Society, University of Canterbury, Christchurch, New Zealand. Young Scientist Seminar, 8 Jun 2005
  • Visnovsky G. (2005) Large-scale production of Serratia entomophila. Cordoba, Argentina: 44th Annual Meeting- Argentine Society for Biochemistry and Molecular Biology research, 1 Dec 2005
  • Visnovsky G. and Merchuk JC. (2004) Optimization of a process for the production of baculovirus in large scale bioreactors. Prague, Czech Republic: 16th International Congress of Chemical and Process Engineering, 22 Aug 2004
  • Visnovsky G. and Merchuk JC. (2003) Influence of dissolved oxygen concentration on the UFL-Ag-286 insect cell growth and polyhedra production: a preliminary study. Rehovot, Israel: Fourth Annual Conference on Active Research by Environmental Sciences Students, CARESS 2003, 11 Jun 2003
  • Visnovsky G. and Merchuk JC. (2003) Kinetics Production of AgMNPV in Optimized Airlift Reactor. Rehovot, Israel: Fourth Annual Conference on Active Research by Environmental Sciences Students, CARESS 2003, 11 Jun 2003
  • Zang YH., Visnovsky G. and Merchuk JC. (2003) Poly-peaks dynamic phenomena in infection process at low multiplicity of infection. Thessaloniki, Greece: 3rd Chemical Engineering Conference for Collaborative Research in Eastern Mediterranean, 15 May 2003
  • Visnovsky G., Claus J. and Merchuk JC. (2002) Culture of insect cells in airlift reactors: study of the influence of geometrical characteristics and gas flow rate on culture behaviour. Iguassu Falls, Brazil: XXXVth Annual Meeting of the Society of Invertebrate Pathology Culture, 17 Aug 2002
  • Visnovsky G., Claus J. and Merchuk JC. (2002) Study of the production of Anticarsia gemmatalis nucleopolyhedrovirus in airlift reactors of different geometrical design. Iguassu Falls, Brazil: XXXVth Annual Meeting of the Society of Invertebrate Pathology Culture, 17 Aug 2002
  • Visnovsky G., Claus J. and Merchuk JC. (2001) Airlift Reactors as a Tool for Insect Cells and Baculovirus Mass Production. Madrid, Spain: 10th European Congress of Biotechnology, ECB10, 8 Jul 2001
  • Visnovsky G., Claus J. and Merchuk JC. (2001) Growth of Spodoptera frugiperda Insect Cells in Airlift Reactors of Different Configuration. Beer-Sheva, Israel: Annual Meeting of the Israel Society for Microbiology (ISM), 26 Feb 2001
  • Visnovsky G., Claus J. and Merchuk JC. (2001) Optimization of the culture of insect cells for the production of viral-based pesticides in airlift reactors: influence of geometrical design and superficial gas velocity. Santa Fe, Argentina: 3rd MercoSur Congress on Process Systems Engineering and 1st MercorSur Congress on Chemical Engineering, ENPROMER, 16 Sep 2002
  • Visnovsky G., Claus J. and Merchuk JC. (2001) The use of concentric-tube airlift reactors for growth of insect cells. Ankara, Turkey: Chemical Engineering Conference for Collaborative Research in Eastern Mediterranean. Middle East Technical University, 20 May 2001
  • Visnovsky G., Merchuk JC., Leguizamon E. and Claus J. (2001) Evaluation of a homologous cell line to develop a process to produce Anticarsia gemmatalis multiple nuclear polyhedrosis virus in vitro. Rehovot, Israel: Third Annual Conference on Active Research by Environmental Sciences Students, CARESS 2001, 14 Jun 2001
  • Merchuk JC., Nakahara T., Visnovsky G., Gluz M. and Mukmenev I. (2000) The use of helical flow promoters for shear sensitive cultures. Dresden, Germany: 5th German-Japanese Symposium of Bubble Columns, 1 Jan 2002
  • Merchuk JC., Visnovsky G., Gluz M. and Mukmenev I. (2000) The Use of Helical Flow Promoters for Shear Sensitive cultures. Beer-Sheva, Israel: Annual Meeting of the Chemical Engineering Society of Israel (ISM), 25 Jun 2000
  • Visnovsky G., Sabtai I. and Merchuk JC. (2000) Importance of Geometrical Design on Performance of Airlift Reactors in the Production of Viral-Based Pesticides. Beer-Sheva, Israel: Annual Meeting of the Israel Society for Microbiology (ISM)., 25 Jun 2000
  • Visnovsky G., Shabtai I. and Merchuk JC. (2000) Production of Viral Insecticides: Importance of Geometrical Design on Performance of Airlift Reactors. Haifa, Israel: XXX Annual Meeting of the Israel Society for Ecology and Environmental, 19 Jun 2000
  • Visnovsky G., Shabtai I. and Merchuk JC. (2000) Study of the Influence of Pluronic F-68 and Silicon Antifoam on the Growth of Insect Cell Cultures. Mendoza, Argentina: XXXV Annual Meeting of the Argentine Society of Investigation in Biochemistry and Molecular Biology, SAIB ’99, 26 Nov 1999
  • Visnovsky G., Shabtai I. and Merchuk J. (1999) Influence of silicone antifoam and pluronic F-68 on insect cells culture growing in airlift reactors. Rehovot, Israel: Second Annual Conference on Active Research by Environmental Sciences Students, CARESS ‘99. Weizmann Institute of Science, 29 May 1999
  • Visnovsky G., Shabtai I. and Merchuk JC. (1999) Biological insecticides: Modeling, optimization and experimental study of the replication of Anticarsia gemmatalis nuclear polyhedrosis virus in insect cell cultures grown in airlift reactors with helical flow promoters. Rehovot, Israel: Annual Meeting of the Israel Society for Microbiology (ISM), Weizmann Institute of Science, 28 Feb 1999
  • Visnovsky G., Shabtai I. and Merchuk JC. (1999) Optimization of Lepidopteran Cell Culture in Airlift Reactors: Influence of Glucose Concentration and Inlet Flow Rate. Mendoza, Argentina: XXXV Annual Meeting of the Argentine Society of Investigation in Biochemistry and Molecular Biology, SAIB ’99, 26 Nov 1999
  • Visnovsky G., Shabtai I. and Merchuk JC. (1999) Use of baculovirus as agent control pest: optimization of virus production in airlift reactors. Jerusalem, Israel: The 7th International Conference of the Israel Society for Ecology and Environmental Quality Sciences on Environmental Challenges for the next Millennium, 13 Jun 1999
  • Visnovsky G., Shabtai I. and Merchuk JC. (1998) Modeling, optimization and experimental study of the replication of Anticarsia gemmatalis nuclear polyhedrosis virus in insect cell cultures grown in airlift reactors with helical flow promoters. Beer-Sheva, Israel: Environment Quality Journeys. The Institutes for Applied Research, Ben-Gurion University of the Negev, 12 Oct 1998
  • Didier C., Visnovsky G. and Claus J. (1997) Optimization of a simple process for the production of polyhedron of Anticarsia gemmatalis nuclear polyhedrosis virus in batch cultures of the cell line IPLB-Sf-21 supplemented with foetal bovine serum. Cordoba, Argentina: XXXIII Annual Meeting Argentine Society for the Investigating in Biochemistry and Molecular Biology, 1 Nov 1997
  • Claus J. and Visnovsky G. (1996) Influence of cultural factors on the multiplication of Anticarsia gemmatalis nuclear polyhedrosis virus in insect cell cultures. Tandil, Argentina: V Argentine Congress of Virology and II Meeting of Latin-American Virology, 1 Apr 1996
  • Claus J., Didier C. and Visnovsky G. (1996) Origin of the limitation in the replication of Anticarsia gemmatalis nuclear polyhedrosis virus in cultures of stationary phase. Tandil, Argentina: V Argentine Congress of Virology and II Meeting of Latin-American Virology, 1 Apr 2006
  • Visnovsky G. and Claus J. (1995) Comparation of different strategies to produce the Anticarsia gemmatalis nuclear polyhedrosis virus in insect cell cultures. Santa Fe, Argentina: Ibero-American Journeys of Bioprocesses, 11 Oct 1995
  • Visnovsky G. and Claus J. (1994) Study of the influence of the infection parameters on the production of Anticarsia gemmatalis nuclear polyhedrosis virus in lepidopteran insect cell cultures. Salto, Uruguay: Seconds Investigations Journeys of the Montevideo Group for Young Investigators, 21 Sep 1994
  • Visnovsky G. and Claus J. (1993) Influence of the time and multiplicity of infection on the batch production of Anticarsia gemmatalis nuclear polyhedrosis virus in lepidopteran insect cell cultures. Santa Fe, Argentina: III Communications Scientific-Technic Journeys. Faculty of Biochemistry and Biological Sciences, National University of Litoral, 11 May 1993
  • Visnovsky G. and Claus J. (1993) Optimization of the variables of infection for the production of baculovirus in cell cultures. Santiago, Chile: III Latin-American Congress of Biotechnology, 16 Nov 1994
  • Visnovsky G. and Claus J. (1993) Production in vitro of the nuclear polyhedrosis virus of Anticarsia gemmatalis, biological control agent of the velvetbean caterpillar. Santa Fe, Argentina: 2nd Scientific and Technologic Journeys, Secretary of Science and Technology, National University of Litoral, Santa Fe, Argentina, 1 Jan 1993
  • Visnovsky G. and Claus J. (1993) Production of Anticarsia gemmatalis nuclear polyhedrosis virus in lepidopteran insect cell cultures: effect of the cellular density. Tucuman, Argentina: IV Argentine Congress of Virology, 5 Sep 1993
  • Visnovsky G. and Claus J. (1992) Multiplication in cell cultures of an isolation of the Anticarsia gemmatalis nuclear polyhedrosis virus. Buenos Aires, Argentina: XIV Annual Scientific Meeting of the Argentine Society of Virology, 10 Dec 1992
Report
  • Jackson T. and Visnovsky G. (2008) Recommendations for development of a microbial bioproduction unit at INIA, Las Brujas, Uruguay.Instituto Nacional de Investigacion Agropecuaria, Uruguay. Commissioned by Instituto Nacional de Investigacion Agropecuaria, Uruguay. 40pp.
  • Visnovsky G. (2007) Cultivation of Brassica sp. and potato (Solanum tuberosum) hairy roots using a bioreactor.Crop and Food Research Ltd. 7pp.
  • Visnovsky G. (2007) High cell density culture of insect cells in airlift reactors of optimized design.AgResearch Ltd. 5pp.
  • Visnovsky G. (2007) Spray-drying fish proteins.Crop and Food Research Ltd. 4pp.
  • Visnovsky G. (2006) Development of a production technology for high cell density and protein expression for Trypsin-producing bacteria.AgResearch. 4pp.
  • Visnovsky G. (2006) Influence of culture medium composition and fermentation strategy on the production of Yersinia entomophila toxins.AgResearch. 6pp.
  • Visnovsky G. (2006) Preliminary studies on culture medium and liquid fermentation strategy development for large-scale production of Sclerotinia sclerotiorium.Dairy InSight. Commissioned by Report prepared for Dairy InSight. 10pp.
  • Visnovsky G. (2006) Production of Paenibacillus polymixa and Bacillus subtilis for seed coating.AgResearch Ltd. 3pp.
  • Visnovsky G. (2005) Optimization of the production of Pantoea agglomerans P10c: preliminary studies.Commissioned by Encote Ltd. 11pp.
  • Visnovsky G. (2005) Preliminary studies on culture medium design and fermentation strategy for large-scale production of Pseudomonas fluorescens F 113.AgResearch Ltd. 10pp.
  • Visnovsky G. (2005) Serratia entomophila: blue print for its production at high densities in bench top reactors.AgResearch Ltd. 5pp.
Thesis / Dissertation
  • Visnovsky G. (2003) Optimization of Anticarsia gemmatalis Nucleopolyhedrovirus in Insect cell Cultures In Airlift Reactors 237pp. Beer-Sheva, Israel. Ben-Gurion University of the Negev.