UC Spark

Professor John Wilson Blunt

Chemistry

Fields of Research

  • Marine natural products
  • Nuclear magnetic resonance spectroscopy

Researcher Summary

Co-leader (with M H G Munro) of Marine Chemistry group, the focus of which is on the isolation and characterisation of novel biologically-active metabolites from marine invertebrates and fungi. Once identified, the compounds are subjected to chemical modifications to establish structure-activity relationships. Much emphasis is placed on the development and exploitation of NMR methods appropriate to the investigation of very small samples.

Subject Area: Disciplines

Key Methodologies

  • Nuclear magnetic resonance spectroscopy

Publications


  • Smith, F., Wood, S., Broady, P., Gaw, S., Williamson, W., Blunt, J. and Munro, M. (2012) Detection of cyanotoxins in New Zealand benthic cyanobacteria. Brisbane, Australia: Society of Environmental Toxicology and Chemistry Australasia Conference (SETAC), 4-6 Jul 2012. (Conference Contribution - Oral presentation)
  • Sultan, S., Shah, S.A.A., Sun, L., Ramasamy, K., Cole, A.L.J., Blunt, J., Munro, M. and Weber, J.-F.F. (2011) Bioactive fungal metabolites of 9PR2 isolated from roots of Callophyllum ferrugineum. International Journal of Pharmacy and Pharmaceutical Sciences 3(Supplement 1): 7-9. (Journal Article)
  • Blunt, J.W., Copp, B.R., Munro, M.H.G., Northcote, P.T. and Prinsep, M.R. (2011) Marine natural products. Natural Product Reports 28(2): 196-268. http://dx.doi.org/10.1039/c005001f. (Journal Article)
  • Blunt, J.W., Copp, B.R., Keyzers, R.A., Munro, M.H.G. and Prinsep, M.R. (2011) Marine natural products. Natural Product Reports 29: 144-222. http://dx.doi.org/10.1039/c2np00090c. (Journal Article)
  • Blunt, J., Buckingham, J. and Munro, M. (2011) Taxonomy and Marine Natural Products Research. In E. Fattorusso, W. H. Gerwick and O. Taglialatela-Scafati (Ed.), Handbook of Marine Natural Products: 1-49. Dordrecht: Springer Science+Business Media B.V. (Chapter in Book)
  • Mahyudin, N.A., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2011) The Isolation of a New S-Methyl Benzothioate Compound from a Marine-Derived Streptomyces sp. Journal of Biomedicine and Biotechnology 2012: 894708. http://dx.doi.org/10.1155/2012/894708. (Journal Article)
  • Blunt, J., Munro, M. and Upjohn, M. (2011) The Role of Databases in Marine Natural Products Research. In E. Fattorusso, W.H. Gerwick and O. Taglialatela-Scafati (Ed.), Handbook of Marine Natural Products: 393-425. Dordrecht: Springer Science+Business Media B.V. http://dx.doi.org/10.1007/978-90-481-3834-0_6. (Chapter in Book)
  • Blunt, J., Cole, T., Munro, M., Sun, L., Weber, J-F.R., Ramasamy, J., Abu Bakar, H. and Abdul Majeed, A.B.B. (2010) Bioactive compounds derived from endophytic Aspergillus fungus strain isolated from Garcinia scortechinii. Patent No. WO 2010062159 A1 20100603, Malaysia, USA, Europe. (Intellectual Property)
  • Grkovic, T., Pearce, A.N., Munro, M.H.G., Blunt, J.W., Davies-Coleman, M.T. and Copp, B.R. (2010) Isolation and Characterization of Diastereomers of Discorhabdins H and K and Assignment of Absolute Configuration to Discorhabdins D, N, Q, S, T, and U. Journal of Natural Products 73(10): 1686-1693. http://dx.doi.org/10.1021/np100443c. (Journal Article)
  • Blunt, J.W., Copp, B.R., Munro, M.H.G., Northcote, P.T. and Prinsep, M.R. (2010) Marine natural products. Natural Product Reports 27(2): 165-237. http://dx.doi.org/10.1039/b906091j. (Journal Article)
  • Devenish, S.R.A., Blunt, J.W. and Gerrard, J.A. (2010) NMR studies uncover alternate substrates for dihydrodipicolinate synthase and suggest that dihydrodipicolinate reductase is also a dehydratase. Journal of Medicinal Chemistry 53(12): 4808-4812. http://dx.doi.org/10.1021/jm100349s. (Journal Article)
  • Sandy, M., Han, A., Blunt, J., Munro, M., Haygood, M. and Butler, A. (2010) Vanchrobactin and Anguibactin Siderophores Produced by Vibrio sp. DS40M4. Journal of Natural Products 73(6): 1038-1043. http://dx.doi.org/10.1021/np900750g. (Journal Article)
  • Hickford, S.J.H., Blunt, J.W. and Munro, M.H.G. (2009) Antitumour polyether macrolides: Four new halichondrins from the New Zealand deep-water marine sponge Lissodendoryx sp. Bioorganic & Medicinal Chemistry 17(6): 2199-2203. http://dx.doi.org/10.1016/j.bmc.2008.10.093. (Journal Article)
  • de Silva, E.D., Geiermann, A-S., Mitova, M.I., Kuegler, P., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2009) Isolation of 2-Pyridone Alkaloids from a New Zealand Marine-Derived Penicillium species. Journal of Natural Products 72(3): 477-479. (Journal Article)
  • Blunt, J.W., Copp, B.R., Hu, W-P., Munro, M.H.G., Northcote, P.T. and Prinsep, M.R. (2009) Marine natural products. Natural Product Reports 26(2): 170-244. http://dx.doi.org/10.1039/b805113p. (Journal Article)
  • Zimmermann, K., Engeser, M., Blunt, J.W., Munro, M.H.G. and Piel, J. (2009) Pederin-Type Pathways of Uncultivated Bacterial Symbionts: Analysis of O-Methyltransferases and Generation of a Biosynthetic Hybrid. Journal of the American Chemical Society 131(8): 2780-2781. http://dx.doi.org/10.1021/ja808889k. (Journal Article)
  • van der Sar, S.A., Lang, G., Mitova, M.I., Blunt, J.W., Cole, A.L.J., Cummings, N.J., Ellis, G. and Munro, M.H.G. (2008) Biosynthesis of spiro-mamakone A, a structurally unprecedented fungal metabolite. Journal of Organic Chemistry 73(21): 8635-8638. http://dx.doi.org/10.1021/jo801564c. (Journal Article)
  • Murphy, A.C., Mitova, M.I., Blunt, J.W. and Munro, M.H.G. (2008) Concise, Stereoselective Route to the Four Diastereoisomers of 4-Methylproline. Journal of Natural Products 71(5): 806-809. http://dx.doi.org/10.1021/np070673w. (Journal Article)
  • Mitova, M.I., Murphy, A.C., Lang, G., Blunt, J.W., Cole, A.L.J., Ellis, G. and Munro, M.H.G. (2008) Evolving Trends in the Dereplication of Natural Product Extracts. 2. The Isolation of Chrysaibol, an Antibiotic Peptaibol from a New Zealand Sample of the Mycoparasitic Fungus Sepedonium chrysospermum. Journal of Natural Products 71(9): 1600-1603. http://dx.doi.org/10.1021/np800221b. (Journal Article)
  • Lang, G., Mayhudin, N.A., Mitova, M.I., Sun, L., van der Sar, S., Blunt, J.W., Cole, A.L.J., Ellis, G., Laatsch, H. and Munro, M.H.G. (2008) Evolving trends in the dereplication of natural product extracts: New methodology for rapid, small-scale investigation of natural product extracts. Journal of Natural Products 71(9): 1595-1599. http://dx.doi.org/10.1021/np8002222. (Journal Article)
  • Blunt, J.W., Copp, B.R., Hu, W-P., Munro, M.H.G., Northcote, P.T. and Prinsep, M.R. (2008) Marine natural prooducts. Natural Product Reports 25(1): 35-94. http://dx.doi.org/10.1039/b701534h. (Journal Article)
  • Sultan, S., Sun, L., Kalavathy, R., Cole, A.L.J., Blunt, J.W., Munro, M.H.G. and Weber, J.F.F. (2007) Bioactive metabolites of endophytic and entomopathogenic fungi of the Malaysian rain forest. Penang, Malaysia: Asian Mycology Congress (AMC 2007) and the Xth International Marine and Freshwater Mycology Symposium (IMFMS), 2-6 Dec 2007. In Asian Mycology Congress and International Marine and Freshwater Mycology Symposium Proceedings 264. (Conference Contribution - Abstract)
  • Blunt, J.W. and Munro, M.H.G. (Ed.) (2007) Dictionary of Marine Natural Products with CD-ROM. Boca Raton: Chapman and Hall/CRC. (Edited Book)
  • Lang, G., Cole, A.L.J., Blunt, J.W., Robinson, W.T. and Munro, M.H.G. (2007) Excelsione, a Depsidone from an Endophytic Fungus Isolated from the New Zealand Endemic Tree Knightia excelsa. Journal of Natural Products 70(2): 310-311. http://dx.doi.org/10.1021/np060202u. (Journal Article)
  • Blunt, J. and Munro, M. (2007) How much is enough? (Invited). Seoul, South Korea: 2nd CMDD Symposium on Marine Natural Products and Drug Discovery (CMDDS 2007), 1-4 Nov 2007. (Conference Contribution - Oral presentation)
  • Sun, L.J., Mahyudin, N.A., Chamyuang, S., Blunt, J., Cole, T., Lang, G., Mitova, M., van der Sar, S. and Munro M. (2007) Less is more: Dereplication and discovery using CapNMR techniques. Queenstown, New Zealand: 12th International Symposium on Marine Natural Products (MaNaProXII), 4-9 Feb 2007. (Conference Contribution - Poster presentation)
  • Hickford, S., Blunt, J.W. and Murray, M.H.G. (2007) Less is More: Microscale NMR Characterisation of New Halichondrins. Queenstown, New Zealand: 12th International Symposium on Marine Natural Products (MaNaProXII), 4-9 Feb 2007. (Conference Contribution - Poster presentation)
  • Mahyudin, N.A., Cole, A., Munro, M., Blunt, J., Cummings, N., Lang, G. and Mitova, M. (2007) Marine invertebrate-derived fungi and their bioactive compounds. Putrajaya, Malaysia: 21st Annual Seminar of the Malaysian Natural Products Society, 22-23 Nov 2005. In Herbal Medicine: nature's gift for health: Proceedings of the 21st Annual Seminar of the Malaysian Natural Products Society 35-47. (Conference Contribution - Paper in published proceedings)
  • Blunt, J.W., Copp, B.R., Hu, W-P., Munro, M.H.G., Northcote, P.T. and Prinsep, M.R. (2007) Marine natural products. Natural Product Reports 24(1): 31-86. http://dx.doi.org/10.1039/b603047p. (Journal Article)
  • Sadiran, S.H., Sultan, S., Sun, L., Cole, A.L.J., Kalavathy, R., Blunt, J.W., Munro, M.H.G. and Weber, J.F.F. (2007) Microbial Metabolites From Malaysian Rain Forest Soil Fungi as a Source of New Drug Candidates. Penang, Malaysia: Asian Mycology Congress (AMC 2007) and the Xth International Marine and Freshwater Mycology Symposium (IMFMS), 2-6 Dec 2007. In Asian Mycology Congress and International Marine and Freshwater Mycology Symposium Proceedings 265. (Conference Contribution - Abstract)
  • Blunt, J.W. and Munro, H.D. (2007) Moving on: the future scale and scope of marine natural products research (Invited). Ischia Island, Italy: V Euroconference on Marine Natural Products (V ECMNP), 16-21 Sep 2007. http://www.ecmnp.org/comprehensive_programme.pdf. (Conference Contribution - Oral presentation)
  • Laatsch, H., Blunt, J.W. and Munro, M.H.G. (2007) New Approaches to Dereplication using AntiMarin and other Tools. Queenstown, New Zealand: 12th International Symposium on Marine Natural Products (MaNaProXII), 4-9 Feb 2007. (Conference Contribution - Oral presentation)
  • Blunt, J.W. (2007) Rapid Discovery Methods for Natural Products (Invited). Bethesda, MD, USA: Natural Products Discovery at the NCI, A Rich Source of New Chemical Diversity and Unique Biological Activities, 7 Jun 2007. http://www.nih.gov/. (Conference Contribution - Oral presentation)
  • Blunt, J.W., Chamyuang, S., Cole, A.L.J., Hickford, S., Lang, G., Mahyudin, N., Mitova, M., Munro, M.H.G., van der Sar, S., Sun, L. and Yusof, M.T. (2007) Simplifying Complexity: The HPLC-Bioactivity-NMR Approach to the Dereplication of Natural Product Extracts (Invited). Penang, Malaysia: Asian Mycology Congress (AMC 2007) and the Xth International Marine and Freshwater Mycology Symposium (IMFMS), 2-6 Dec 2007. http://www.ippp.um.edu.my/amc2007/doc/AMC%20PROGRAM%20NOV%2027.doc. (Conference Contribution - Oral presentation)
  • Mitova, M.I., Lang, G., Murphy, A., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2006) Alteration of secondary metabolite profile of fungi in response to a competitor's challenge. Rotorua, New Zealand: NZIC Conference 2006 "Back to the Basics: From Small Molecules to Materials and Surfaces", 2-6 Dec 2006. In Proceedings of the NZIC 2006 II - Posters 14. (Conference Contribution - Poster presentation)
  • Lang, G., Cole, A.L.J., Blunt, J.W. and Munro, M.H.G. (2006) An Unusual Oxalylated Tetramic Acid from the New Zealand Basidiomycete Chamonixia pachydermis. Journal of Natural Products 69(1): 151-153. http://dx.doi.org/10.1021/np050488n. (Journal Article)
  • Lang, G., Mitova, M.I., Ellis, G., Van der Sar, S.A., Phipps, R.K., Blunt, J.W., Cummings, N.J., Cole, A.L.J. and Munro, M.H.G. (2006) Bioactivity Profiling Using HPLC/Microtiter-Plate Analysis: Application to a New Zealand Marine Alga-Derived Fungus, Gliocladium sp. Journal of Natural Products 69(4): 621-624. http://dx.doi.org/10.1021/np0504917. (Journal Article)
  • Mitova, M.I., Stuart, B.G., Cao, G.H., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2006) Chrysosporide, a cyclic pentapeptide from a New Zealand sample of the fungus Sepedonium chrysospermum. Journal of Natural Products 69(10): 1481-1484. http://dx.doi.org/10.1021/np060137o. (Journal Article)
  • Mitova, M.I., Lang, G., Blunt, J.W., Cummings, N.J., Cole, A.L.J., Robinson, W.T. and Munro, M.H.G. (2006) Cladobotric Acids A-F: New Cytotoxic Polyketides from a New Zealand Cladobotryum sp. Journal of Organic Chemistry 71(2): 492-497. http://dx.doi.org/10.1021/jo051883l. (Journal Article)
  • Dabydeen, D.A., Burnett, J.C., Bai, R.L., Verdier-Pinard, P., Hickford, S.J.H., Pettit G.R., Blunt., J.W., Munro., M.H.G., Gussio., R., Hamel., E., Robinson. and W.T. (2006) Comparison of the Activities of the Truncated Halichondrin B Analog NSC 707389 (E7389) with Those of the Parent Compound and a Proposed Binding Site on Tubulin. Molecular Pharmacology 70(6): 1866-1875. http://dx.doi.org/10.1124/mol.106.026641. (Journal Article)
  • Blunt, J.W. (2006) Dereplication to Discovery: New Methodology for Rapid, Small-Scale Investigation of Fungal Metabolites. Arlington, VA, USA: 47th Annual Meeting of American Society of Pharmacognosy, 5-9 Aug 2006. (Conference Contribution - Oral presentation)
  • Blunt, J.W. (2006) Dereplication to Discovery: New Methodology for Rapid, Small-Scale Investigation of Metabolites from Malaysian and New Zealand Fungi. Kuala Lumpur, Malaysia: 22nd Annual Seminar of the Malaysian Natural Products Society (MNPS): Beyond Medicinal Plants, 8-10 Nov 2006. (Conference Contribution - Oral presentation)
  • Lang, G., Mitova, M., van der Sar, S., Mahyudin, N.A., Cummings, N., Abdullah, N., Blunt, J.W., Cole, A.L.J., Din, L.B., Vikneswary, S. and Munro, M.H.G. (2006) Dereplication, Databases and Discovery: the Probing of Fungal Chemodiversity. Kyoto, Japan: IUPAC International Conference on Biodiversity and Natural Products (ICOB-5 & ISCNP-25), 23-28 Jul 2006. (Conference Contribution - Oral presentation)
  • Blunt, J., Cole, T., Ellis, G., Kuegler, P., Laatsch, H., Lang, G., Mitova, M., Mahyudin, N.A., Munro, M., Phipps, R., van der Sara, S. and Sun, J.L. (2006) Downsizing Discovery: Bioactive Natural Product Dereplication and Discovery using Diminutive Samples. Rotorua, New Zealand: NZIC Conference 2006 "Back to the Basics: From Small Molecules to Materials and Surfaces", 2-6 Dec 2006. In Proceedings of the NZIC 2006 I - Talks 39. (Conference Contribution - Oral presentation)
  • Munro, M., Blunt, J. and Cole, T. (2006) Drugs from the Sea? Linking Biodiversity and Bioprospecting with Drug Discovery. Colombo, Sri Lanka: International Symposium on Herbal Medicine, Phytopharmaceuticals and Other Natural Products: Trends and Advances, 15-17 Jun 2005. In Herbal Medicine, Phytopharmaceuticals and other Natural Products: Trends and Advances 323-333. (Conference Contribution - Paper in published proceedings)
  • Devenish, S.R.A., Hill, J.B., Blunt, J.W., Morris, J.C. and Munro, M.H.G. (2006) Dual side-reactions limit the utility of a key polymer therapeutic precursor. Tetrahedron Letters 47(17): 2875-2878. http://dx.doi.org/10.1016/j.tetlet.2006.02.131. (Journal Article)
  • de Silva, E.D., van der Sar, S.A., Santha, R.G.L., Wijesundera, R.L.C., Cole, A.L.J., Blunt, J.W. and Munro M.H.G. (2006) Lanostane triterpenoids from the Sri Lankan basidiomycete Ganoderma applanatum. Journal of Natural Products 69(8): 1245-1248. http://dx.doi.org/10.1021/np0602214. (Journal Article)
  • de Silva, E.D., Santha, R.G.L., Wijesunder, R.L.C., Cole, A.L.G., Blunt, J.W. and Munro, M.H.G. (2006) Lanostane-Type Triterpenoids from the Fungus Ganoderma applanatum Collected in Sri Lanka. Colombo, Sri Lanka: International Symposium on Herbal Medicine, Phytopharmaceuticals and Other Natural Products: Trends and Advances, 15-17 Jun 2005. In Herbal Medicine, Phytopharmaceuticals and other Natural Products: Trends and Advances 233-237. (Conference Contribution - Paper in published proceedings)
  • Blunt, J.W., Copp, B.R., Munro, M.H.G., Northcote, P.T. and Prinsep, M.R. (2006) Marine natural products. Natural Product Reports 23(1): 26-78. http://dx.doi.org/10.1039/b502792f. (Journal Article)
  • Lang, G., Mitova, M., van der Sar, S., de Silva, E.D., Mahyudin, N.A., Cummings, N.J., Cole, A.L.J., Blunt, J.W. and Munro, M.H.G. (2006) Probing Fungal Chemodiversity. Marine-Derived vs. Endophytic vs. Entomopathogenic. Rotorua, New Zealand: NZIC Conference 2006 "Back to the Basics: From Small Molecules to Materials and Surfaces", 2-6 Dec 2006. In Proceedings of the NZIC 2006 II - Posters 12. (Conference Contribution - Poster presentation)
  • Chen, C-H., Lang, G., Mitova, M.I., Murphy, A.C., Cole, A.L.J., Din, L.B., Blunt, J.W. and Munro, M.H.G. (2006) Pteratides I-IV, new Cytotoxic Cyclodepsipeptides from the Malaysian Basidiomycete Pterula sp. Journal of Organic Chemistry 71(21): 7947-7951. http://dx.doi.org/10.1021/jo060843u. (Journal Article)
  • Lang, G., Mitova, M.I., Cole, A.L.J., Din, L.B., Vikineswary, S., Abdullah, N., Blunt, J.W. and Munro, M.H.G. (2006) Pterulamides I-VI, Linear Peptides from a Malaysian Pterula sp. Journal of Natural Products 69(10): 1389-1393. http://dx.doi.org/10.1021/np0600245. (Journal Article)
  • van der Sar, S.A., Blunt, J.W. and Munro, M.H.G. (2006) spiro-Mamakone A: A unique relative of the Spirobisnaphthalene class of compounds. Organic Letters 8(10): 2059-2061. http://dx.doi.org/10.1021/ol060434k. (Journal Article)
  • Murphy, A., Muscroft-Taylor, A., Devenish, S., Munro, M. and Blunt, J. (2006) Towards the Synthesis of spiro-Mamakone A. Rotorua, New Zealand: NZIC Conference 2006 "Back to the Basics: From Small Molecules to Materials and Surfaces", 2-6 Dec 2006. In Proceedings of the NZIC 2006 II - Posters 67. (Conference Contribution - Poster presentation)
  • Lee, M.B., Storer, M.K., Blunt, J.W. and Lever, M. (2006) Validation of 1H NMR spectroscopy as an analytical tool for methylamine metabolites in urine. Clinica Chimica Acta 365(1-2): 264-269. http://dx.doi.org/10.1016/j.cca.2005.09.004. (Journal Article)
  • Dalsgaard, P.W., Blunt, J.W., Munro, M.H.G., Frisvad, J.C. and Christophersen, C. (2005) Communesins G and H, new alkaloids from the psychrotolerant fungus Penicillium rivulum. Journal of Natural Products 68: 258-261. (Journal Article)
  • Van der Sar, S.A., Blunt, J.W., Cole, A.L.J., Din, L.B. and Munro, M.H.G. (2005) Dichlorinated pulvinic acid derivative from a Malaysian Scleroderma sp. Journal of Natural Products 68: 1799-1801. (Journal Article)
  • Lang, G., Pinkert, A., Blunt, J.W. and Munro, M.H.G. (2005) Discorhabdin W, the first dimeric discorhabdin. Journal of Natural Products 68: 1796-1798. (Journal Article)
  • Lang, G., Blunt, J.W., Cummings, N.J., Cole, A.L.J. and Munro, M.H.G. (2005) Hirsutide, a Cyclic Tetrapeptide from a Spider-Derived Entomopathogenic Fungus, Hirsutella sp. Journal of Natural Products 68: 1303-1305. (Journal Article)
  • Lang, G., Blunt, J.W., Cummings, N.J., Cole, A.L.J. and Munro, M.H.G. (2005) Paecilosetin, a new bioactive fungal metabolite from a New Zealand isolate of Paecilomyces farinosus. Journal of Natural Products 68: 810-811. (Journal Article)
  • Miller, I.J. and Blunt, J.W. (2005) The application of 13C NMR spectroscopy to the red algal polysaccharides of selected New Zealand species of Lomentaria. Botanica Marina 48: 167-174. (Journal Article)
  • Miller, I.J. and Blunt, J.W. (2005) The structure of sulfated galactans from selected species of New Zealand Champia. Botanica Marina 48: 127-136. (Journal Article)
  • Miller, I.J. and Blunt, J.W. (2005) The structure of the galactan from Aeodes nitidissima (Halymeniales, Rhodophyta). Botanica Marina 48: 137-142. (Journal Article)
  • Lee, M.B., Blunt, J.W., Lever, M. and George, P.M. (2004) A nuclear-magnetic-resonance-based assay for betaine–homocysteine methyltransferase activity. Analytical Biochemistry 330: 199-205. (Journal Article)
  • Phipps, R.K., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2004) Anthracycline derivatives from a marine-derived New Zealand Streptomycete. Arkivoc 2004(x): 94-100. (Journal Article)
  • Jiao, W., Feng, Y., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2004) Chaetoglobosins Q, R, and T, Three Further New Metabolites from Chaetomium globosum. Journal of Natural Products 67(10): 1722-1725. http://dx.doi.org/10.1021/np030460g. (Journal Article)
  • Overy, D.P. and Blunt, J.W. (2004) Corymbiferan Lactones from Penicillium hordei: Stimulation of Novel Phenolic Metabolites Using Plant Tissue Media. Journal of Natural Products 67: 1850-1853. (Journal Article)
  • Jiao, W., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2004) Fumagiringillin, a New Fumagillin Derivative from a Strain of the Fungus Aspergillus fumigatus. Journal of Natural Products 67(8): 1434-1437. http://dx.doi.org/10.1021/np049893p. (Journal Article)
  • Feng, Y., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2004) Novel Cytotoxic Thiodiketopiperazine Derivatives from a Tilachlidium sp. Journal of Natural Products 67(12): 2090-2092. doi:10.1021/np030326w. (Journal Article)
  • Hickford, S.J.H., Kuepper, F.C., Zhang, G., Carrano, C.J., Blunt, J.W. and Butler, A. (2004) Petrobactin Sulfonate, a New Siderophore Produced by the Marine Bacterium Marinobacter hydrocarbonoclasticus. Journal of Natural Products 67: 1897-1899. (Journal Article)
  • Dalsgaard, P.W., Blunt, J.W., Munro, M.H.G., Larsen, T.O. and Christophersen, C. (2004) Psychrophilin B and C: cyclic nitropeptides from the psychrotolerant fungus Penicillium rivulum. Journal of Natural Products 67: 1950-1952. (Journal Article)
  • Miller, I.J. and Blunt, J.W. (2003) Two fucoidans: structural constancy and variation. In R.O. Chapman, R.J. Anderson, V.J. Vreeland and I.R. Davison (Ed.), Proceedings of the 17th International Seaweeds Symposium: 221-228. Oxford: Oxford University Press. (Chapter in Book)
  • Feng, Y., Blunt, J.W., Cole, A.L.J., Cannon, J.F., Robinson, W.T. and Munro, M.H.G. (2003) Two Novel Cytotoxic Cyclodepsipeptides from a Mycoparasitic Cladobotryum sp. Journal of Organic Chemistry 68(5): 2002-2005. doi:10.1021/jo0263059. (Journal Article)
  • Harwood, D.T., Urban, S., Blunt, J.W. and Munro, M.H.G. (2003) β-Carboline alkaloids from a New Zealand marine bryozoan, Cribricellina cribraria. Natural Product Research 17(1): 15-19. (Journal Article)
  • Feng, Y., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2002) A Novel Cyclodepsipeptide, HA23, from a Fusarium sp. Organic Letters 4(12): 2095-2096. doi:10.1021/ol0260167. (Journal Article)
  • Blunt, J. (2002) Adding value to marine toxins - invited lecture. Cairns, Australia: 6th Asia-Pacific Congress on Animal, Plant and Microbial Toxins, July 2002. (Conference Contribution - Other)
  • Munro, M.H.G., Blunt, J.W., Cole, A.L.J., Cummings, N. and Feng, Y. (2002) Compound. Patent No. 521300 (Provisional Patent Application Number), New Zealand. (Intellectual Property)
  • Urban, S., Blunt, J.W. and Munro, M.H.G. (2002) Coproverdine: A novel cytotoxic marine alkaloid from a New Zealand ascidian. J.Nat. Prod. 65: 1371-3. (Journal Article)
  • Miller, I.J. and Blunt, J.W. (2002) Evaluation of the structure of the polysaccharides from Chondria macrocarpa and Ceramium rubrum as determined by 13C NMR spectroscopy. Bot. Mar. 45: 1-8. (Journal Article)
  • Blunt, J.W., Copp, B.R., Munro, M.H.G., Northcote, P.T. and Prinsep, M.R. (2002) Marine Natural Products. Journal of Natural Products 20: 1-48. (Journal Article)
  • Miller, I.J. and Blunt, J.W. (2002) Mobility of sulfate ester during structural determinations of red algal galactans. Bot. Mar. 45: 559-65. (Journal Article)
  • Feng, Y., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2002) The Isolation of Two New Chromone Derivatives from the New Zealand Fungus Tolypocladium extinguens. Journal of Natural Products 65(11): 1681-1682. doi:10.1021/np020160j. (Journal Article)
  • Feng, Y., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2002) Three novel cytochlasins X, Y, and Z from Pseudeurotium zonatum. J. Nat. Prod. 65: 1274-7. (Journal Article)
  • Urban, S., Blunt, J.W. and Munro, M.H.G. (2001) A Novel, Cytotoxic Marine Alkaloid from a New Zealand Ascidian. Oaxaca, Mexico: 42nd Annual Meeting of the American Society of Pharmacognosy, 14-18 July 2001. (Conference Contribution - Other)
  • Munro, M.H.G., Blunt, J.W., Urban, S. and Gravalos, D.G. (2001) Antitumor carbazoles, and coproverdine isolation. Patent No. PCT/GB01/05523, International. (Intellectual Property)
  • Nicholas, G.M., Blunt, J.W. and Munro, M.H.G. (2001) Cortamidine oxide, a novel disulfide metabolite from the New Zealand basidiomycete (mushroom) Cortinarius species. N.Z.. J. Nat. Prod 64(3): 341-4. (Journal Article)
  • Phipps, R.K., Jiao,W., Feng, Y., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2001) Discovery and development of compounds with pharmaceutical potential from New Zealand fungi. Okinawa, Japan: 10th International Symposium on Marine Natural Products, 24-29 June 2001. (Conference Contribution - Other)
  • Wood, J.E., Lever, M. and Blunt, J.W. (2001) Modified Betaines and Water. J. Biochem. Mol Biol. & Biophys. 5: 252-92. (Journal Article)
  • Lever, M., Blunt, J.W. and Maclagan, R.G.A.R. (2001) Some ways of looking at compensatory kosmotropes and different water environments. Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology 130(3): 471-486. doi:10.1016/S1095-6433(01)00416-0. (Journal Article)
  • Urban, S., Hickford, S.J.H., Blunt, J.W., Munro, M.H.G. and Kelly, M. (in part). (2000) Bioactive marine alkaloids.. : 765-807. (Chapter in Book)
  • Simpson, J.S., Garson, M.J., Blunt, J.W., Munro, M.H.G. and Hooper, J.N.A. (2000) Mycalamides C and D, cytotoxic compounds from the marine sponge Stylinos n. species.. J. Nat. Prod. 63(5): 704-6. (Journal Article)
  • Miller, I.J. and Blunt, J.W. (2000) New 13C NMR methods for determining the structure of algal polysaccharides. Part I. The effect of substitution on the chemical shifts of simple diad galactans.. Bot. Mar 43(3): 239-50. (Journal Article)
  • Miller, I.J. and Blunt, J.W. (2000) New 13C NMR methods for determining the structure of algal polysaccharides. Part II. Galactans consisting of mixed diols.. Bot. Mar 43(3): 251-61. (Journal Article)
  • Miller, I.J. and Blunt, J.W. (2000) New 13C NMR methods for determining the structure of algal polysaccharides. Part III. The structure of the polysaccharide from Cladhymenia oblongifolia.. Bot. Mar. 43(3): 263-71. (Journal Article)
  • Phipps, R.K., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (2000) New Zealand Bioactive marine microorganisms-approach to dereplication. Townsville, Australia: IMBC 2000, 29 September - 4 October 2000. (Conference Contribution - Other)
  • Hart, J.B., Lill, R.E., Hickford, S.J.H., Blunt, J.W. and Munro, M.H.G. (2000) The halichondrins: Chemistry, biology, supply and delivery. In Fusetani, N. (Ed.), Drugs Sea: 134-53. Basel, Switzerland: S Karger AG. (Chapter in Book)
  • Bokesch, H.R., Blunt, J.W., Westergaard, C.K., Cardellina II, J.H., Johnson, T.R., Michael, J.A., McKee, T.C., Hollingshead, M.G. and Boyd, M.R. (1999) Alertenone, a dimer of suberosenone from Alertigorgia sp.. J. Nat. Prod. 62: 633--5. (Journal Article)
  • Munro, M.H.G., Blunt, J.W., Walker, J.R.L., Ward, J.M., Wood, J.E. and Perry, N.B. (1999) Biologically active compounds from Ozothamnus leptophyllus. New Zealand Journal of Botany 37: 167--74. (Journal Article)
  • Munro, M.H.G., Dumdei, E.J., Hickford, S.J., Lill, R.E., Li, S., Battershill, C.N. and Duckworth, A.R. (1999) Discovery and development of marine compounds with pharmaceutical potential. In Osinga, R., Tramper, J., Burgess, J. G. and Wijffels, R. (Ed.), Marine Bioprocess Engineering, Progress in Industrial Microbiology: 27-46. Amsterdam: Elsevier Science. (Chapter in Book)
  • Fuller, R.W., Blunt, J.W., Boswell, J.L., Cardellina II, J.H. and Boyd, M.R. (1999) Guttiferone F, the first prenylated benzophenone from Allanblackia stuhlmannii.. J. Nat. Prod 62: 130-2. (Journal Article)
  • Munro, M.H.G., Blunt, J.W., Dumdei, E.J., Hickford, S.J.H., Lill, R.E., Li, S., Battershill, C.N. and Duckworth, A.R. (1999) The discovery and development of marine compounds with pharmaceutical potential.. J. Biotechnol. 70: 15-25. (Journal Article)
  • Randall, K., Lever, M., Blunt, J.W. and Chambers, S.T. (1998) Counteraction of urea denaturation by glycine betaine and other kosmotropes.. J. Biochem. Mol. Biol. & Biophys. 2: 51-8. (Journal Article)
  • Miller, I.J. and Blunt, J.W. (1998) Desulfation of algal galactans. Carbohydrate Res. 309: 39-43. (Journal Article)
  • Bokesch, H.R., Young, S.M., McKee, T.C., Blunt, J.W. and Boyd, M.R. (1998) Lambertianoside, a novel phenylglycoside from Eugenia lambertiania.. Nat. Prod. Lett. 11: 211-6. (Journal Article)
  • Perry, N.B., Ellis, G., Blunt, J.W., Haystead, T.A.J., Lake, R.J. and Munro, M.H.G. (1998) Okadaic acid in New Zealand sponges: Detection by cytotoxicity, protein phosphatase inhibition and immunoassay techniques. Nat. Prod Lett. 11: 305-12. (Journal Article)
  • Blunt, J.W. (1998) Old problems - new solutions. Plenary lecture.. Townsville, Australia: 9th International Symposium on Marine Natural Products, July 1998. (Conference Contribution - Other)
  • Dumdei, E.J., Blunt, J.W., Munro, M.H.G., Battershill, C.N. and Page, M.J. (1998) The whys and whats of sponge chemistry: why chemists extract sponges and what problems does this cause? In Watanabe, Y. and Fusetani, N. (Ed.), Sponge Sciences. Multidisciplinary Perspectives.: 353-64. Tokyo: Springer. (Chapter in Book)
  • Li, S., Dumdei, E.J., Blunt, J.W., Munro, M.H.G., Robinson, W.T. and Pannell, L.K. (1998) Theonellapeptolide IIIe, a new cyclic peptolide from the New Zealand deep water sponge, Lamellomorpha strongylata.. J. Nat. Prod. 61: 724-8. (Journal Article)
  • Litaudon, M., Hickford, S.J.H., Lill, R.E., Lake, R.J., Blunt, J.W. and Munro, M.H.G. (1997) Antitumor polyether macrolides: new and hemisynthetic halichondrins from the New Zealand deep-water sponge Lissodendoryx sp.. J. Org. Chem. 62: 1868-71. (Journal Article)
  • Stewart, M., Fell, P.M., Blunt, J.W. and Munro, M.H.G. (1997) Avarol and related compounds from the New Zealand sponge Dysidea sp.. Aust. J. Chem 50: 341-347. (Journal Article)
  • Abell, A.D., Blunt, J.W., Foulds, G.J. and Munro, M.H.G. (1997) Chemistry of the mycalamides: antiviral and antitumour compounds from a New Zealand marine sponge. Part 6. The synthesis and testing of analogues of the C7-C10 fragment. Journal of Chemical Society, Perkin Transactions 1 : 1647-1654. (Journal Article)
  • Nicholas, G.M., Blunt, J.W., Cole, A.L.J. and Munro, M.H.G. (1997) Investigation of the New Zealand basidiomycete Favolaschia calocera: Revision of the structures of 9-methoxystrobilurins K and L, strobilurin D, and hydroxystrobilurin D. Tetrahedron Lett. 38: 7465-8. (Journal Article)
  • Dumdei, E.J., Blunt, J.W., Munro, M.H.G. and Pannell, L.K. (1997) Isolation of calyculins, calyculinamides, and swinholide H from the New Zealand deep-water marine sponge Lamellomorpha strongylata.. J. Org. Chem. 62: 2636-9. (Journal Article)
  • Carr, A.C., Winterbourn, C.C., Blunt, J.W., Phillips, A.J. and Abell, A.D. (1997) Nuclear Magnetic Resonance characterization of 6alpha-chloro-5beta-cholestane-3beta,5-diol formed from the reaction of hypochlorous acid with cholesterol.. Lipids 32(4): 363-367. (Journal Article)
  • Stewart, M., Blunt, J.W., Munro, M.H.G., Robinson, W.T. and Hannah, D.J. (1997) The absolute stereochemistry of the New Zealand shellfish toxin gymnodimine. Tetrahedron Lett 38: 4889-90. (Journal Article)