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Researcher
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BlueFern
Professor Timothy David
BlueFern Super Computer
Phone: +64 3 364 2987 ext. 43210
Office: NZi3 217
Fields of Research
Mathematical and numerical models of cardiovascular blood flow
Computational Physiology
Dynamics of Coupled Cells
Cerebral Autoregulation
Researcher Summary
Research interests include:
- Neurovascular coupling
- Dynamics of large vascular trees
Subject Area: Disciplines
Engineering and Technology:
Bioengineering
; Computer & Software Engineering
Health and Health Sciences:
Biomedical
Biology: Molecular, Cellular and Whole Organism Biology:
Cell Biology
Research Groups
Biomathematics Research Centre
Brain's Trust (BT)
Centre for Bioengineering
Affiliations
Institute of Mathematics and Its Application (IMA)
(Professional Organisation): Fellow (FIMA)
Institute of Mechanical Engineers (IMechE)
(Professional Organisation): Member (MIMechE)
Institute of Physics and Engineering in Medicine (IPEM)
(Professional Organisation): Fellow (FIPEM)
Institution of Professional Engineers New Zealand (IPENZ)
(Professional Organisation): Fellow
Research Service
Director, BlueFern (2010-present)
Publications
Docherty, P.D., Chase, J.G. and David, T. (2012) Characterisation of the iterative integral parameter identification method.
Medical and Biological Engineering and Computing
50(2): 127-134.
http://dx.doi.org/10.1007/s11517-011-0851-y
.
(Journal Article)
Shaikh, S.A. and David, T. (2012)
Massively Parallel Coupled Cell Dynamics for Atherosclerotic regions.
Berlin, Germany: 10th International Symposium: Computer Method in Biomechanics and Biomedical Engineering, 11 Apr 2012.
(Oral Presentation)
Safaeian, N., Sellier, M. and David, T. (2011) A computational model of hemodynamic parameters in cortical capillary networks.
Journal of Theoretical Biology
271(1): 145-156.
http://dx.doi.org/10.1016/j.jtbi.2010.11.038
.
(Journal Article)
Shaikh, M., Wall, D.J.N. and David, T. (2011) Macro-scale phenomena of arterial coupled cells: a Massively Parallel simulation.
Journal of the Royal Society Interface
9(70): 972-987.
http://dx.doi.org/10.1098/rsif.2011.0453
.
(Journal Article)
Farr, H. and David, T. (2011) Models of neurovascular coupling via potassium and EET signalling.
Journal of Theoretical Biology
286: 13-23.
http://dx.doi.org/10.1016/j.jtbi.2011.07.006
.
(Journal Article)
Nock, V., Alkaisi, M.M., Blaikie, R.J. and David, T. (2011)
Optical Sensors for Spatially-Resolved Measurement of Oxygen in Microfluidic Devices.
Las Vegas, NV, USA: 55th International Confrence on Electron, Ion, Photon Beam Technology and Nanofabrication (EIPBN), 31 May-3 Jun 2011.
(Conference Contribution - Oral presentation)
David, T. and Moore, S. (2011) System Level Acceleration with Blue Gene/L: Grand Challenge Problems in Physiological Multi-Scale Modelling. In I. Foster, W. Gentzsch, L. Grandinetti and G.R. Joubert (Ed.),
High Performance Computing: From Grids and Clouds to Exascale
: 246-266. Amsterdam: IOS Press.
http://dx.doi.org/10.3233/978-1-60750-803-8-246
.
(Chapter in Book)
David, T., van Kempen, T., Huang, H. and Wilson, P. (2011) The geometry and dynamics of binary trees.
Mathematics and Computers in Simulation
81(7): 1464-1481.
http://dx.doi.org/10.1016/j.matcom.2010.04.020
.
(Journal Article)
Imai, Y., Sato, K., Ishikawa, T., Comerford, A., David, T. and Yamaguchi, T. (2010) ATP Transport in Saccular Cerebral Aneurysms at Arterial Bends.
Annals of Biomedical Engineering
38(3): 927-934.
http://dx.doi.org/10.1007/s10439-009-9864-1
.
(Journal Article)
Farr, H. and David, T. (2010)
Computational Models of Metabolic Autoregulaiton in the Cerebro-vasculature.
Valencia, Spain: 9th International Symposium of Computer Methods in Biomechanics & Biomedical Engineering 2010 (CMBBE2010), 24-27 Feb 2010.
(Conference Contribution - Full conference paper)
Yamamoto, M. and David, T. (2010)
Endothelial Nitric Oxide Concentration and its Implications in Carotid Artery atherosclerosis - An integrated cell/hemodynamics approach.
Singapore: 6th World Congress of Biomechanics, Aug 2010. In WCB 2010 414-417.
(Conference Contribution - Paper in published proceedings)
Safaeian, N., David, T. and Sellier, M. (2010)
General Model for the Cortical Capillary Network of the Human Cortex and an Investigation on Functional Reactivity of the Cortical Capillary Network to the Different Blood Inflows.
Singapore: 6th World Congress on Biomechanics, 1-6 Aug 2010. 31 450-453.
(Conference Contribution - Paper in published proceedings)
Buchmann, N.A., Yamamoto, M., Jermy, M.C. and David T. (2010) Particle Image Velocimetry (PIV) and Computational Fluid Dynamics (CFD) Modelling of Carotid Artery Haemodynamics under Steady Flow: A Validation Study.
Journal of Biomechanical Science and Engineering
5(4): 421-426.
http://dx.doi.org/10.1299/jbse.5.421
.
(Journal Article)
Shaikh, M.A., David, T. and Wall, D.J.N. (2010)
Spatial Effects of Oscillations in Coupled Cells.
Valencia, Spain: 9th International Symposium of Computer Methods in Biomechanics & Biomedical Engineering 2010 (CMBBE2010), 24-27 Feb 2010. In Proceedings 6pp.
(Conference Contribution - Paper in published proceedings)
David, T. (2010)
The Challenge of Multiple Scales in the Biological Sciences: Applications in Cerebro-vascular Perfusion.
Valencia, Spain: 9th International Symposium of Computer Methods in Biomechanics & Biomedical Engineering 2010 (CMBBE2010), 24-27 Feb 2010.
(Conference Contribution - Full conference paper)
David, T., Alzaidi, S. and Farr, H. (2009)
Computational models of functional hyperaemia in the cerebro-vasculature.
Cairns, Australia: 18th World IMACS Congress and MODSIM09 International Congress on Modelling and Simulation, 13-17 Jul 2009. In Modelling and Simulation Society of Australia and New Zealand and International Association for Mathematics and Computers in Simulation 656-663.
http://www.mssanz.org.au/modsim09/B4/david.pdf
.
(Conference Contribution - Paper in published proceedings)
Shaikh, M.A., David, T. and Wall, D.J.N. (2009)
Effects of spatially varying agonist concentration on calcium signalling in coupled vascular endothelial and smooth muscle cells.
Cairns, Australia: 18th World IMACS Congress and MODSIM09 International Congress on Modelling and Simulation, 13-17 Jul 2009. In Proceedings of the 18th World IMACS Congress and MODSIM09 International Congress on Modelling and Simulation 627-633.
http://www.mssanz.org.au/modsim09/B2/shaikh.pdf
.
(Conference Contribution - Paper in published proceedings)
Nock, V., Blaikie, R.J. and David, T. (2009)
In-situ Optical Oxygen Sensing for Bio-artificial Liver Bioreactors.
Singapore: 13th International Conference on Biomedical Engineering (ICBME), 3-6 Dec 2008. In IFMBE Proceedings 23 778-781.
http://dx.doi.org/10.1007/978-3-540-92841-6_191
.
(Conference Contribution - Paper in published proceedings)
Nock, V., Blaikie, R.J. and David, T. (2009)
Oxygen Control For Bioreactors And In-vitro Cell Assays.
Dunedin, New Zealand: 4th International Conference on Advanced Materials and Nanotechnology (AMN-4), 8-12 Feb 2009. In AIP Conference Proceedings, Advanced Materials and Nanotechnology: Proceedings of the International Conference 1151(1) 67-70.
http://dx.doi.org/10.1063/1.3203249
.
(Conference Contribution - Paper in published proceedings)
David, T. (2009) System Level Accelerator with Blue Gene: A Heterogeneous Computing Model for Grand Challenge Problems. In W. Gentzsch, L. Grandinetti and G. Joubert (Ed.),
High Speed and Large Scale Scientific Computing
: 365-379. Amsterdam: IOS Press.
http://dx.doi.org/10.3233/978-1-60750-073-5-365
.
(Chapter in Book)
Moore, S.M. and David, T. (2008) A model of autoregulated blood flow in the cerebral vasculature.
Journal of Engineering in Medicine
222(4): 513-530.
http://dx.doi.org/10.1243/09544119JEIM298
.
(Journal Article)
Comerford, A.P. and David, T. (2008) Computer Model of Nucleotide Transport in a Realistic Porcine Aortic Trifurcation.
Annals of Biomedical Engineering
36(7): 1175-1187.
http://dx.doi.org/10.1007/s10439-008-9493-0
.
(Journal Article)
David, T., Alzaidi, S., Chatelin, R. and Farr, H. (2008)
Coupled Autoregulation Models.
Singapore: 13th International Conference on Biomedical Engineering (ICBME 2008), 3-6 Dec 2008. In IFMBE Proceedings 23(5) 1896-1899.
http://dx.doi.org/10.1007/978-3-540-92841-6_470
.
(Conference Contribution - Paper in published proceedings)
Kleinstreuer, N., David, T., Plank, M.J. and Endre, Z. (2008) Dynamic myogenic autoregulation in the rat kidney: a whole organ model.
American Journal of Physiology: Renal Physiology
294(6): F1453-F1464.
http://dx.doi.org/10.1152/ajprenal.00426.2007
.
(Journal Article)
Comerford, A., Plank, M.J. and David, T. (2008) Endothelial Nitric Oxide Synthase and Calcium Production in Arterial Geometries: An Integrated Fluid Mechanics/Cell Model.
Journal of Biomechanical Engineering
130(1): 011010.
http://dx.doi.org/10.1115/1.2838026
.
(Journal Article)
Comerford, A. and David, T. (2008)
eNOS concentrations in complex arterial blood flow.
Pittsburgh, USA: 16th International Conference on Mechanics in Medicine and Biology, 2008.
(Conference Contribution - Paper in published proceedings)
Nock, V., Blaikie, R.J. and David, T. (2008)
Generation and Detection of Laminar Flow with Laterally-Varying Oxygen Concentration Levels.
San Diego, CA, USA: 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2008), 12-16 Oct 2008. In Proceedings of the 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences 1 299-301.
www.rsc.org/binaries/LOC/2008/PDFs/Papers/101_0927.pdf
.
(Conference Contribution - Paper in published proceedings)
David, T. and Moore, S. (2008) Modeling perfusion in the cerebral vasculature.
Medical Engineering & Physics
30(10): 1227-1245.
http://dx.doi.org/10.1016/j.medengphy.2008.09.008
.
(Journal Article)
Nock, V.M., Blaikie, R.J. and David, T. (2008) Patterning, integration and characterisation of polymer optical oxygen sensors for microfluidic devices.
Lab on a Chip
8: 1300-1307.
http://dx.doi.org/10.1039/b801879k
.
(Journal Article)
Alastruey, J., Moore, S.M., Parker, K.H. and David, T. (2008) Reduced modelling of blood flow in the cerebral circulation: Coupling 1-D, 0-D and cerebral auto-regulation models.
International Journal for Numerical Methods in Fluids
56(8): 1061-1067.
http://dx.doi.org/10.1002/fld.1606
.
(Journal Article)
David, T. (2008)
System Level Accelerator with Blue Gene: A Heterogeneous Computing Model for Grand Challenge Problems.
Cetraro, Italy: HPC2008 workshop, 2008.
(Conference Contribution - Paper in published proceedings)
Imai, Y., Sato, K., Ishikawa, T., Comerford, A., David, T. and Yamaguchi, T. (2007)
CFD Study on Mass Transport to Saccular Aneurysms at Arterial Bend.
Tokyo, Japan: Third Asian Pacific Conference on Biomechanics (AP Biomech 2007), 5-8 Nov 2007.
(Conference Contribution - Oral presentation)
Kleinstreuer, N.C., David, T., Plank, M. and Endre, Z.H. (2007)
Dynamic Myogenic Autoregulation in the Rat Kidney: A Whole-Organ Mathematical Model.
Tokyo, Japan: Third Asian Pacific Conference on Biomechanics (AP Biomech 2007), 5-8 Nov 2007.
http://www.apb07.iis.u-tokyo.ac.jp/
.
(Conference Contribution - Oral presentation)
Buchmann, N.A., Jermy, M.C. and David, T. (2007)
Experimental Investigation of Blood Flow in the Brain by means of Particle Image Velocimetry - A preliminary Study.
Shanghai, China: Fifth International Conference on Fluid Mechanics (ICFM-V), 15-19 Aug 2007.
http://icfm5.sjtu.edu.cn/
.
(Conference Contribution - Full conference paper)
Nock, V.M., Blaikie, R.J. and David, T. (2007)
Fabrication of Optical Grayscale Masks for Tapered Microfluidic Devices.
Copenhagen, Denmark: 33rd International Conference on Micro- and Nano-Engineering (MNE), 23-26 Sep 2007.
http://www.mne07.org/
.
(Conference Contribution - Oral presentation)
Nock, V.M., Blaikie, R.J. and David, T. (2007)
Micro-patterning of polymer-based optical oxygen sensors for lab-on-chip applications.
Canberra, Australia: Microelectronics, MEMS, and Nanotechnology 2007: BioMEMS and Nanotechnology III Conference 6799, 5-7 Dec 2007. In Proceedings of SPIE 6799(BioMEMS and Nanotechnology III) 67990Y.
http://dx.doi.org/10.1117/12.759023
.
(Conference Contribution - Paper in published proceedings)
Plank, M.J., Comerford, A., Wall, D.J.N. and David, T. (2007) Modelling the Early Stages of Atherosclerosis. In A. Deutsch, L. Brusch, H. Byrne, G. de Vries and H. Herzel (Ed.),
Mathematical Modeling of Biological Systems, Volume I: Cellular Biophysics, Regulatory Networks, Development, Biomedicine, and Data Analysis
: 263-274. Boston: Birkhauser.
(Chapter in Book)
Moore, S.M., Fink, J.N. and David, T. (2007)
Patient Specific Response to Stenosis in the Circle of Willis.
Tokyo, Japan: Third Asian Pacific Conference on Biomechanics (AP Biomech 2007), 5-8 Nov 2007.
http://www.apb07.iis.u-tokyo.ac.jp/
.
(Conference Contribution - Oral presentation)
Nock, V.M., Blaikie, R.J. and David, T. (2007)
Plasma Patterning of Fluorescence-based Oxygen Sensors.
Copenhagen, Denmark: 33rd International Conference on Micro- and Nano-Engineering (MNE), 23-26 Sep 2007.
http://www.mne07.org/
.
(Conference Contribution - Oral presentation)
Plank, M.J., Wall, D.J.N. and David, T. (2007) The role of endothelial calcium and nitric oxide in the localisation of atherosclerosis.
Mathematical Biosciences
207(1): 26-39.
http://dx.doi.org/10.1016/j.mbs.2006.08.017
.
(Journal Article)
Moore, S., David, T., Chase, J.G., Arnold, J. and Fink, J. (2006) 3D Models of Blood Flow in the Cerebral Vasculature.
Journal of Biomechanics
39(8): 1454-1463.
http://dx.doi.org/10.1016/j.jbiomech.2005.04.005
.
(Journal Article)
Plank, M.J., Wall, D.J.N. and David, T. (2006) Atherosclerosis and calcium signalling in endothelial cells.
Progress in Biophysics and Molecular Biology
91(3): 287-313.
http://dx.doi.org/10.1016/j.pbiomolbio.2005.07.005
.
(Journal Article)
Moore, S. and David, T. (2006) Auto-Regulated Blood Flow in the Cerebral-Vasculature.
Journal of Biomechanical Science and Engineering
1(1): 93-106.
(Journal Article)
Nock, V., Blaikie, R. and David, T. (2006)
Bioartificial Livers - A Place in Therapy?
University of Canterbury, Christchurch, New Zealand: The 2006 MacDiarmid Institute Student and Postdoctoral Symposium, 29-30 Nov 2006.
(Conference Contribution - Poster presentation)
Plank, M.J., Comerford, A., David, T. and Wall, D.J.N. (2006) Concentration of blood-borne agonists at the endothelium.
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
462(2066): 671-688.
http://dx.doi.org/10.1098/rspa.2005.1591
.
(Journal Article)
Comerford, A., David, T. and Plank, M.J. (2006) Effects of arterial bifurcation geometry on nucleotide concentration at the endothelium.
Annals of Biomedical Engineering
34(4): 605-617.
http://dx.doi.org/10.1007/s10439-005-9046-8
.
(Journal Article)
Moorhead, K.T., Chase, J.G., David, T. and Arnold, J. (2006) Metabolic Model of Autoregulation in the Circle of Willis.
Journal of Biomechanical Engineering
128(3): 462-466.
http://dx.doi.org/10.1115/1.2187048
.
(Journal Article)
Kim, C.S., Kiris, C., Kwak, D. and David, T. (2006) Numerical Simulation of Local Blood Flow in the Carotid and Cerebral Arteries under Altered Gravity.
Journal of Biomechanical Engineering
128(2): 194-202.
http://dx.doi.org/10.1115/1.2165691
.
(Journal Article)
Verma, H., Hagedorn, P. and David, T. (2005)
Computing the power imparted by the fluid on an oscillating cylinder in cross-flow: Some results and many questions.
Santorini, Greece: Fourth Symposium on Bluff Body Wakes and Vortex-Induced Vibrations, 21-24 Jun 2005.
(Conference Contribution - Full conference paper)
Moorhead, K.T., Moore, S.M., Chase, J.G., David, T. and Fink, J. (2005) Impact of decentralised control in cerebral blood flow auto-regulation using 1D and 3D models.
International Journal of Intelligent Systems Technologies and Applications
1(1/2): 95-110.
http://www.inderscience.com/storage/f862911131054127.pdf
.
(Journal Article)
Plank, M.J., Comerford, A., David, T. and Wall, D.J.N. (2005)
Modelling the localisation of cardiovascular disease.
Singapore: 12th International Conference on Biomedical Engineering (ICBME 2005), 7-10 Dec 2005. In Proceedings of the 12th International Conference on Biomedical Engineering (ICBME 2005) 1B1-01.
http://www.icbme.org/
.
(Conference Contribution - Paper in published proceedings)
Farnell, D.J.J., David, T. and Barton, D.C. (2005) Numerical Model of Self-propulsion in a Fluid.
Journal of The Royal Society Interface
2: 79-88.
DOI: 10.1098/rsif.2005.0027
.
(Journal Article)
Moore, S.M., Moorhead, K.T., Chase, J.G., David, T. and Fink, J. (2005) One-Dimensional and Three-Dimensional Models of Cerebrovascular Flow.
Journal of Biomechanical Engineering
127(3): 440-449.
(Journal Article)
Moore, S., David, T., Chase, J.G. and Fink, J. (2004)
3D Time-dependent Models of Blood Flow in the Cerebral Vasculature.
Osaka, Japan: 1st Asian-Pacific Conference on Biomechanics, 25-28 Mar 2004. 51-52.
(Conference Contribution - Other)
David, T. (2004)
ATP/ADP Concentrations at the Endothelium.
Osaka, Japan: 1st Asian-Pacific Conference on Biomechanics, 25-28 Mar 2004. 73-74.
(Conference Contribution - Other)
Farnell, D.J.J., David, T. and Barton, D.C. (2004) Coupled States of Flapping Flags.
Journal of Fluids and Structures
19: 29-36.
(Journal Article)
Skilbeck, C., Walker, P.G., David, T. and Nash, G. (2004) Disturbed flow promotes deposition of leukocytes from flowing whole blood in a model of a damaged vessel wall.
British Journal of Haematology
126(3): 418-427.
(Journal Article)
Farnell, D.J.J., David, T., Callaghan, F. and Barton, D.C. (2004)
Flexible Membranes in Flowing Fluids.
Paris, France: Fluid Induced Vibration, 6-9 Jul 2004. 155-160.
(Conference Contribution - Other)
Pagiwoko, C.P., David, T. and Van Houten, E.E.W. (2004)
Flow Induced Vibration of a Flexible Filament.
Lisbon, Portugal: 4th International Conference on Engineering Computational Technology, 7-9 Sep 2004. 61-62.
(Conference Contribution - Other)
Moorhead, K.T., Doran, C.V., Chase, J.G. and David,T. (2004) Lumped Parameter and Feedback Control Models of the Auto-Regulatory Response in the Circle of Willis.
Computer Methods in Biomechanics and Biomedical Engineering
7(3): 121-130.
(Journal Article)
Sung Kim, C., Kris, C., Kwak, D. and David, T. (2004)
Numerical Models of Human Circulatory System under Altered Gravity: Brain Circulation.
Reno, USA: 42nd AIAA Aerospace Sciences Meeting, 5-8 Jan 2004. 1-12.
(Conference Contribution - Other)
Farnell, D.J.J., David, T. and Barton, D.C. (2004) Numerical Simulations of a filament in a flowing soap film.
International Journal of Numerical Methods in Fluids
44: 313-330.
(Journal Article)
Callaghan, F. and David, T. (2004)
Numerical Simulations of an Idealised Artificial Heart Valve.
Osaka, Japan: 1st Asian-Pacific Conference on Biomechanics, 25-28 Mar 2004. 63-64.
(Conference Contribution - Other)
Jordan, A., David,T., Homer-Vanniasinkam, S., Graham, A. and Walker, P.G. (2004) The Effects of Margination and Red Cell Augmented Platelet Diffusivity on Platelet Adhesion in Complex Flow.
Biorheology
41(5): 641-653.
(Journal Article)
David, T., Brown, M. and Ferrandez, A. (2003) Auto-regulation and blood flow in the cerebral circulation.
International Journal for Numerical Methods in Fluids
43: 701-713.
(Journal Article)
Moorhead, K.T., Doran, C.V., Chase, J.G. and David, T. (2003)
Lumped Parameter and Feedback Control Models of the Auto-Regulatory Response in the Circle of Willis.
Sydney, Australia: World Congress on Medical Physics and Biomedical Engineering (WC2003), 24-29 Aug 2003. 4.
(Conference Contribution - Other)
Smith, B.W., Chase, J.G., Nokes, R.I., Shaw, G.M. and David, T. (2003) Velocity profile method for time varying resistance in minimal cardiovascular system models.
Physics in Medicine and Biology
48(20): 3375-3387.
(Journal Article)
David, T. (2003) Wall Shear Stress Modulation of ATP/ADP Concentration at the Endothelium.
Annals of Biomedical Engineering
31(10): 1231-1237.
(Journal Article)
Pleydell, C.P., David, T., Smye, S.W. and Berridge, D.C. (2002) A Mathematical Model of Post-Canalisation Thrombolysis.
Physics in Medicine and Biology.
47: 209--224.
(Journal Article)
David, T. and Walker, P.G. (2002) Activation and extinction models for platelet adhesion.
Biorheology
39(3-4): 475-481.
(Journal Article)
Walker, P.G., Alshorman, A., Westwood, S. and David, T. (2002) Adhesion of leukocytes under oscillating stagnation point conditions: a numerical study.
Biorheology
39(3-4): 293-298.
(Journal Article)
David, T. and Groot PG, Walker PG. (2002) Boundary layer type solutions for initial platelet activation and deposition..
Journal of Theoretical Medicine
4(2): 95-108.
(Journal Article)
Ferrandez, A., David, T. and Brown, M.D. (2002) Numerical Models of Auto-regulation and Blood Flow in the Cerebral Circulation.
Computer Methods in Biomechanics and Biomedical Engineering
5(1): 7--19.
(Journal Article)
David, T. and Ferrandez, A. (2001)
Blood Flow in the Cerebral Arterial Tree and its Response to Pressure Fluctuations.
Snowbird, UTAH: ASME Summer Bioengineering Conference, June 2001.
(Conference Contribution - Other)
David, T. and Ferrandez, A. (2001)
Computational Models of Blood Flow in the Cerebral Arterial Tree.
Zurich: Conference of the European Society of Biomechanics, 'July 2001'.
(Conference Contribution - Other)
Skilbeck, C., Westwood, S., Walker, P.G., David, T. and Nash, G.B. (2001) Dependence of adhesive behaviour of neutrophils on local fluid dynamics in a region with recirculating flow.
Biorheology
(38): 213--227.
(Journal Article)
Fenlon, A.J. and David, T. (2001) Numerical Models for the Simulation of Flexible Leaflet Heart Valves Part 1- Computational Methods.
Computer Methods in Biomechanics and Biomedical Engineering
4: 323--339.
(Journal Article)
Fenlon, A.J. and David, T. (2001) Numerical Models for the Simulation of Flexible Leaflet Heart Valves Part 2- Valve Studies.
Computer Methods in Biomechanics and Biomedical Engineering
4(6): 449--462.
(Journal Article)
Thomas, S.J., David, T. and Walker, P.G. (2001) Platelet Deposition in Stagnation Point Flow: An Analytical and Computational Simulation.
Medical Engineering and Physics
23(5): 299--312.
(Journal Article)
Skilbeck, C., Westwood, S., Walker, P.G., David, T. and Nash, G.B. (2001) Population of the Vessel Wall by Leukocytes binding to P-Selectin in a model of disturbed arterial flow Arteriosclerosis.
Arteriosclerosis, Thrombosis and Vascular Biology
2001(21): 1294--1300.
(Journal Article)
Skilbeck C, Westwood S., Walker, P.G., David, T. and Nash, G.B. (2001) Relation between adhesive behavior of neutrophils and local fluid dynamics in a region with recirculating bloodflow..
Biorheology
38: 213-227.
(Journal Article)
David,T. (2000)
Activation and Extinction Models for Platelet Adhesion.
Eindhoven, The Netherlands: 4th European Fluid Mechanics Conference (EUROMECH), 'November 2000'.
(Conference Contribution - Other)
Fenlon, A.J., David, T. and Walton, J.P.R.B. (2000)
An Integrated Visualization and Design Toolkit for Flexible Prosthetic Heart Valves.
Proceedings of the 11th Annual IEEE Conference on Visualization (Visualization 2000), 2000. 453--456..
(Conference Contribution - Other)
David, T. (2000)
Blood Platelet Activation and Deposition Models.
Chicago: International Congress of Theoretical and Applied Mechanics, 'August 2000'.
(Conference Contribution - Other)
Pederson EM, Walker P., Ferrandez, A. and David, T. (2000) Comparison of computerised fluid dynamics and high resolution phase contrast MRI for wall shear stress estimation in vivo..
ISMRM Denver
(Journal Article)
Ferrandez, A. and David, T. (2000)
Computational Models of Blood Flow in the Circle of Willis.
Proceedings of the 4th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering., 2000'. 701-706.
(Conference Contribution - Other)
Ferrandez, A., David, T., Bamford, J., Scott, J. and Guthrie, A. (2000) Computational Models of Blood Flow in the Circle of Willis.
Computer Methods in Biomechanics and Biomedical Engineering
4: 1--26.
(Journal Article)
Ferrandez, A., David, T., Pedersen, E.M. and Wu, S. (2000)
Computational Models of the Circle of Willis and the Visibility of Small Cerebral Arteries.
World Congress on Medical Physics and Biomedical Engineering, 'July 2000'.
(Conference Contribution - Other)
Fenlon, A., David, T. and Barton, D.C. (2000)
Fluid Structure Interaction of Flexible Leaflet Heart Valves.
World Congress on Medical Physics and Biomedical Engineering, 'July 2000'.
(Conference Contribution - Other)
Thomas, S., David, T. and Walker, P.G. (2000)
Models of Platelet Deposition in Stagnation Point Flow.
2000'. 743-749.
(Conference Contribution - Other)
Wright, H., Brodlie, K. and David, T. (2000)
Navigating High-Dimensional Spaces to Support Design Steering.
Proceedings of the 11th Annual IEEE Conference on Visualization (Visualization 2000), 2000. 291--296..
(Conference Contribution - Other)
David, T. (2000) Numerical and Analytical Models of Artificial Heart Valves. In P. Verdonck and K. Perktold (Ed.),
Intra and Extracorporeal Cardiovascular Fluid Dynamics
: 177-208.WIT Press.
(Chapter in Book)
Thomas, S., David, T. and Walker, P.G. (1999) Platelet Deposition in Stagnation Point Flow: An Analytical and Computational Simulation. In Sajjadi, Thomas, Nash and Rampling (Ed.),
Proceedings of the 1998 IMA Conference 'Cardiovascular Flow Modelling and Measurement with Application to Clinical Medicine'
: 49-58.
(Chapter in Book)
Thomas, S., David, T. and Walker, PG. (1999)
Platelet deposition in stagnation point flow: an analytical and computational simulation..
IMA Conference: Cardiovascular flow modelling and measurement with application to clinical medicine., 1999.
(Conference Contribution - Other)
David, T. (1999) Simulation of Time-dependent Blood Flow past Valve Prostheses. In X.Y. Xu and M.W Collins (Ed.),
Bench-top Experiments and Numerical Models In Comparison of Computational Predictions with In Vitro and In Vivo Data.
: 85-130.WIT Press.
(Chapter in Book)
David, T., Smye, S., James, T. and Dabbs, T. (1998)
A Model for the Fluid Motion of Vitreous Humour of the Human Eye during Saccadic Motion.
Sapporo, Japan: 3rd World Congress of Biomechanics, August 1998.
(Conference Contribution - Other)
David, T., Smye, S., James, T. and Dabbs, T. (1998)
Analytical models of Wall Shear Stress in the Human Eye during Saccadic Motion.
Sapporo, Japan: 3rd World Congress of Biomechanics, August 1998.
(Conference Contribution - Other)
Bagnall, R., David, T. and Fisher, J. (1998)
Complex Time dependent Flow in the Neighbourhood of the Aortic Root.
Sapporo, Japan: 3rd World Congress of Biomechanics, August 1998.
(Conference Contribution - Other)
David, T., Smye, S., James, T. and Dabbs, T. (1998) Fluid Motion of Posterior Vitreous Humour during Saccadic Movement.
Physics in Medicine and Biology
43: 1385--1399.
(Journal Article)
Fenlon, A.J. and David, T. (1998)
Time Dependent Dynamic Analysis of Flexible Heart Valves.
Sapporo, Japan: 3rd World Congress of Biomechanics, August 1998.
(Conference Contribution - Other)
Tan, M. and David, T. (1998)
Vortex Interaction in Bi-Leaflet Prosthetic Heart Valves.
Sapporo, Japan: 3rd World Congress of Biomechanics, August 1998.
(Conference Contribution - Other)
Smye, S.E., Berridge, D., Ouriel, K., Parkin, A. and David, T. (1997) Assessing Clot Lysis Strategies using Simplified Mathematical Models.
Journal of Medical Engineering and Technology
21: 121-125.
(Journal Article)
King, M.K., David, T. and Fisher, J. (1997) Three dimensional study of the effect of two leaflet opening angles on the time dependent flow through a bileaflet mechanical heart valve.
Medical Engineering and Physics
19: 235--241.
(Journal Article)
David, T., Smye, S., James, T. and Dabbs, T. (1997) Time-Dependent Stress and Displacement of the Eye Wall Tissue of the Human Eye.
Medical Engineering and Physics
19(2): 131--139.
(Journal Article)