UC Spark

Dr Aaron James Le Compte

Mechanical Engineering

Fields of Research

  • Glucose-insulin system modelling

Researcher Summary

Research interests and activities include modelling and control of the glucose regulatory system in intensive care. This research develops methodologies to identify patient metabolic state in both adults and prematurely born infants. Forecasting techniques are developed to predict evolution of metabolism for control. Simulation studies are used to optimise control strategies to adapt to local clinical practices. Pilot clinical trials are conducted to verify simulation outputs and prepare glucose control systems for wider adoption into typical clinical usage.

Other research interests include assessing sensitivity to insulin as a marker of patient illness, modelling the cardiovascular and renal systems, and investigating the wider cost and health benefits of improved glucose control for critically ill patients.

Subject Area: Disciplines

Research Projects

Key Methodologies

  • Modelling of physiological control systems
  • In-silico simulation of therapies for clinical intensive care
  • Conduct and analyse pilot clinical trials
  • Develop software and systems for everyday clinical use

Publications


  • Le Compte, A.J., Pretty, C.G., Lin, J., Shaw, G.M., Lynn, A. and Chase, J.G. (2013) Impact of variation in patient response on model-based control of glycaemia in critically ill patients. Computer Methods and Programs in Biomedicine 109(2): 211-219. http://dx.doi.org/10.1016/j.cmpb.2011.08.007. (Journal Article)
  • Hewett, J., Rodgers, G.W., Chase, J.G., Le Compte, A.J., Pretty, C.G. and Shaw, G.M. (2012) Assessment of SOFA score as a diagnostic indicator in intensive care medicine. Budapest, Hungary: 8th IFAC Symposium on Biological and Medical Systems (BMS12), 29-31 Aug 2012. In Biological and Medical Systems 8(1) 467-472. http://dx.doi.org/10.3182/20120829-3-HU-2029.00035. (Conference Contribution - Paper in published proceedings)
  • LeCompte, A.J., Shaw, G.M. and Chase, J.G. (2012) Benchtop to bedside to worldwide: Implementing model-based glycemic control in intensive care. Budapest, Hungary: 8th IFAC Symposium on Biological and Medical Systems (BMS12), 29-31 Aug 2012. (Conference Contribution - Other)
  • Penning, S., Signal, M., Preiser, J.C., Shaw, G.M., Le Compte, A.J., Pretty, C.G., Desaive, T. and Chase, J.G. (2012) Cumulative time in band (cTIB): Glycemic level, variability and patient outcome all in one. Lisbon, Portugal: 25th Annual Congress of the European Society of Intensive Care Medicine (ESICM), 13-17 Oct 2012. (Conference Contribution - Abstract)
  • Ward, L., Steel, J., LeCompte, A.J., Evans, A., Tan, C.S., Penning, S., Shaw, G.M., Desaive, T. and Chase, J.G. (2012) Data entry errors and design for model-based tight glycemic control in critical care. Journal of Diabetes Science and Technology 6(1): 135-143. (Journal Article)
  • Dickson, J.L., Le Compte, A.J., Floyd, R.P., Chase, J.G., Lynn, A. and Shaw, G.M. (2012) Development and optimisation of stochastic targeted (STAR) glycaemic control for neonatal intensive care. Budapest, Hungary: 8th IFAC Symposium on Biological and Medical Systems (BMS12), 29-31 Aug 2012. In Biological and Medical Systems 8(1) 319-324. http://dx.doi.org/10.3182/20120829-3-HU-2029.00034. (Conference Contribution - Paper in published proceedings)
  • Fisk, L., Le Compte, A.J., Shaw, G.M., Penning, S., Desaive, T. and Chase, J.G. (2012) Development and pilot trial results of stochastic targeted (STAR) glycemic control in a medical ICU. Budapest, Hungary: 8th IFAC Symposium on Biological and Medical Systems (BMS12), 29-31 Aug 2012. In Biological and Medical Systems 8(1) 301-306. http://dx.doi.org/10.3182/20120829-3-HU-2029.00044. (Conference Contribution - Paper in published proceedings)
  • Penning, S., Le Compte, A.J., Signal, M., Massion, P., Preiser, J.C., Shaw, G.M., Desaive, T. and Chase, J.G. (2012) Does tight glycemic control positively impact on patient mortality? Brussels, Belgium: 32nd Symposium on Intensive Care and Emergency Medicine (ISICEM), 20-23 Mar 2012. In Critical Care 16(Supplement 1) P176. (Conference Contribution - Abstract)
  • Pretty, C.G., Lin, J., Le Compte, A.J., Shaw, G.M. and Chase, J.G. (2012) Endogenous insulin secretion in critically ill patients. Brussels, Belgium: 32nd Symposium on Intensive Care and Emergency Medicine (ISICEM), 20-23 Mar 2012. In Critical Care 16(Supplement 1) P168. (Conference Contribution - Abstract)
  • Fisk, L., Willis, J., Le Compte, A.J., Shaw, G.M. and Chase, J.G. (2012) Glargine and glycemia: Pitfalls and perils. Budapest, Hungary: 8th IFAC Symposium on Biological and Medical Systems (BMS12), 29-31 Aug 2012. In Biological and Medical Systems 8(1) 254-259. http://dx.doi.org/10.3182/20120829-3-HU-2029.00063. (Conference Contribution - Paper in published proceedings)
  • Le Compte, A.J., Pretty, C.G., Shaw, G.M. and Chase, J.G. (2012) Glucometer accuracy and implications for clinical studies. Brussels, Belgium: 32nd Symposium on Intensive Care and Emergency Medicine (ISICEM), 20-23 Mar 2012. In Critical Care 16(Supplement 1) P173. (Conference Contribution - Abstract)
  • Signal, M., Le Compte, A.J., Harris, D.L., Weston, P.J., Harding, J.E. and Chase, J.G. (2012) Impact of calibration algorithms on hypoglycaemia detection in newborn infants using continuous glucose monitors. Budapest, Hungary: 8th IFAC Symposium on Biological and Medical Systems (BMS12), 29-31 Aug 2012. In Biological and Medical Systems 8(1) 242-247. http://dx.doi.org/10.3182/20120829-3-HU-2029.00031. (Conference Contribution - Paper in published proceedings)
  • Pretty, C.G., Le Compte, A.J., Shaw, G.M. and Chase, J.G. (2012) Impact of sensor and measurment timing errors on model-based insulin sensitivity. Budapest, Hungary: 8th IFAC Symposium on Biological and Medical Systems (BMS12), 29-31 Aug 2012. In Biological and Medical Systems 8(1) 355-360. http://dx.doi.org/10.3182/20120829-3-HU-2029.00046. (Conference Contribution - Paper in published proceedings)
  • Penning, S., Massion, P., Le Compte, A.J., Desaive, T. and Chase, J.G. (2012) Insulin kinetics during hyper-insulinemia euglycemia therapy (HIET). Budapest, Hungary: 8th IFAC Symposium on Biological and Medical Systems (BMS12), 29-31 Aug 2012. In Biological and Medical Systems 8(1) 295-300. http://dx.doi.org/10.3182/20120829-3-HU-2029.00037. (Conference Contribution - Paper in published proceedings)
  • Ward, L., Steel., J., LeCompte, A.J., Evans, A., Tan, C-S., Penning, S., Shaw, G.M., Desaive, T. and Chase, J.G. (2012) Interface design and human factors considerations for model-based tight glycemic control in critical care. Journal of Diabetes Science and Technology 6(1): 125-134. (Journal Article)
  • Fisk, L., Clarkson, S., Le Compte, A.J., Shaw, G.M. and Chase, J.G. (2012) Nutrition rates and impact of clinical stoppages for two AGC protocols. Budapest, Hungary: 8th IFAC Symposium on Biological and Medical Systems (BMS12), 29-31 Aug 2012. In Biological and Medical Systems 8(1) 307-312. http://dx.doi.org/10.3182/20120829-3-HU-2029.00060. (Conference Contribution - Paper in published proceedings)
  • Jamaludin, U.K., Docherty, P.D., Chase, J.G., Le Compte, A.J. and Shaw, G.M. (2012) Observation of changes in model-based insulin sensitivity during haemodialysis transitions for critically ill patients. Budapest, Hungary: 8th IFAC Symposium on Biological and Medical Systems (BMS12), 29-31 Aug 2012. In Biological and Medical Systems 8(1) 349-354. http://dx.doi.org/10.3182/20120829-3-HU-2029.00021. (Conference Contribution - Paper in published proceedings)
  • Jamaludin, U.K., Docherty, P.D., Chase, J.G., Le Compte, A.J., Shaw, G.M., Desaive, T. and Preiser, J.C. (2012) Observation of incretin effects during enteral feed transitions of critically ill patients. e-SPEN Journal 74(4): e154-e159. http://dx.doi.org/10.1016/j.clnme.2012.05.002. (Journal Article)
  • Le Compte, A.J., Lynn, A.M., Lin, J., Pretty, C.G., Shaw, G.M. and Chase, J.G. (2012) Pilot study of a model-based approach to blood glucose control in very-low-birthweight neonates. BMC Pediatrics 12(117) http://dx.doi.org/10.1186/1471-2431-12-117. (Journal Article)
  • Fisk, L.M., Le Compte, A.J., Shaw, G.M., Penning, S., Desaive, T. and Chase, J.G. (2012) Pilot trial of STAR in the medical ICU. Brussels, Belgium: 32nd Symposium on Intensive Care and Emergency Medicine (ISICEM), 20-23 Mar 2012. In Critical Care 16(Supplement 1) P172. (Conference Contribution - Abstract)
  • Penning, S., Le Compte, A.J., Massion, P., Moorhead, K.T., Pretty, C.G., Preiser, J.C., Shaw, G.M., Suhaimi, F., Desaive, T. and Chase, J.G. (2012) Second Pilot Trials of the STAR-Liege Protocol for Tight Glycemic Control in Critically Ill Patients. BioMedical Engineering OnLine 11: 58. http://dx.doi.org/10.1186/1475-925X-11-58. (Journal Article)
  • Evans, A., Le Compte, A.J., Tan, C-S., Ward, L., Steel, J., Pretty, C.G., Penning, S., Suhaimi, F., Shaw, G.M., Desaive, T. and Chase, J.G. (2012) Stochastic targeted (STAR) glycemic control: Design, safety and performance. Journal of Diabetes Science and Technology 6(1): 102-115. (Journal Article)
  • Suhaimi, F., Chase, J.G., Le Compte, A.J. and Shaw, G.M. (2012) The influence of clinical experience in sepsis diagnosis. Melbourne, Australia: College of Intensive Care Medicine Annual Scientific Meeting (CICM-ASM 2012), 25-27 May 2012. (Conference Contribution - Other)
  • Signal, M., Le Compte, A.J., Harris, D.L., Weston, P.J., Harding, J.E. and Chase, J.G. (2012) Using a stochastic model to detect unusual continuous glucose monitor behaviour in newborn infants. Budapest, Hungary: 8th IFAC Symposium on Biological and Medical Systems (BMS12), 29-31 Aug 2012. In Biological and Medical Systems 8(1) 248-253. http://dx.doi.org/10.3182/20120829-3-HU-2029.00032. (Conference Contribution - Paper in published proceedings)
  • Signal, M., Le Compte, A., Harris, D.L., Weston, P.J., Harding, J.E. and Chase, G. (2012) Using Stochastic Modelling to Identify Unusual Continuous Glucose Monitor Measurements and Behavior in Newborn Infants. BioMedical Engineering OnLine 11(45) http://dx.doi.org/10.1186/1475-925X-11-45. (Journal Article)
  • Pretty, C.G., Le Compte, A.J., Chase, J.G., Shaw, G.M., Preiser, J-C., Penning, S. and Desaive, T. (2012) Variability of insulin sensitivity during the first 4 days of critical illness: Implications for tight glycaemic control. Annals of Intensive Care 2(17): Online. http://dx.doi.org/10.1186/2110-5820-2-17. (Journal Article)
  • Lin, J., Razak, N.N., Pretty, C.G., Le Compte, A.J., Docherty, P.D., Parente, J.D., Shaw, G.M., Hann, C.E. and Chase, J.G. (2011) A physiological Intensive Control Insulin-Nutrition-Glucose (ICING) model validated in critically ill patients. Computer Methods and Programs in Biomedicine 102(2): 192-205. http://dx.doi.org/10.1016/j.cmpb.2010.12.008. (Journal Article)
  • Penning, S., Desaive, T., Massion, P., Le Compte, A.J., Moorhead, K.T., Pretty, C.G., Shaw, G.M. and Chase, J.G. (2011) Accurate Glycemic Control in Critically Ill Patients: The Stochastic Targeted Framework. San Francisco, CA, USA: 11th Annual Diabetes Technology Meeting (DTM2011), 2011. (Conference Contribution - Abstract)
  • Fisk, L.M., Chase, J.G., Le Compte, A.J. and Shaw, G.M. (2011) Accurate Glycemic Control with STAR. San Francisco, CA, USA: 11th Annual Diabetes Technology Meeting (DTM2011), 2011. (Conference Contribution - Abstract)
  • Lin, J., Parente, J.D., Chase, J.G., Shaw, G.M., Blakemore, A.J., LeCompte, A.J., Pretty, C., Razak, N.N., Lee, D.S., Hann, C.E. and Wang, S-H. (2011) Development of a model-based clinical sepsis biomarker for critically ill patients. Computer Methods and Programs in Biomedicine (102): 149-155. http://dx.doi.org/10.1016/j.cmpb.2010.04.002. (Journal Article)
  • LeCompte, A.J., Chase, J.G., Lynn, A., Hann, C.E., Shaw, G.M. and Lin, J. (2011) Development of Blood Glucose Control for Extremely Premature Infants. Computer Methods and Programs in Biomedicine 102(2): 181-191. http://dx.doi.org/10.1016/j.cmpb.2010.03.010. (Journal Article)
  • Stevenson, D.J., Revie, J.A., Chase, J.G., Le Compte, A.J., Shaw, G.M., Lambermont, B.C. and Desaive, T. (2011) Diagnosing pulmonary embolism from a model-based cardiac driver function. Taupo, New Zealand: Australia-New Zealand Intensive Care Society (ANZICS) ASM, 31 Mar-1 Apr 2011. (Conference Contribution - Oral presentation)
  • Pretty, C.G., Docherty, P.D., Pfeiffer, L., Jamaludin, U., Shaw, G.M., Le Compte, A.J. and Chase, J.G. (2011) Endogenous insulin secretion and suppression during and after sepsis in critically ill patients - implications for TGC protocols. Brussels, Belgium: 31st International Symposium on Intensive Care and Emergency Medicine (31st ISICEM), 22-25 Mar 2011. 1pp. http://ccforum.com/supplements/notes/ccv15s1-info.pdf. (Conference Contribution - Abstract)
  • Chase, J.G., Le Compte, A.J., Penning, S., Moorhead, K.T., Massion, P., Preiser, J.C., Pretty, C.G., Shaw, G.M. and Desaive, T. (2011) Enhanced insulin sensitivity variability in the first 3 days of ICU stay: Implications for Tight Glycemic Control. Brussels, Belgium: 31st International Symposium on Intensive Care and Emergency Medicine (31st ISICEM), 22-25 Mar 2011. 1pp. http://ccforum.com/content/15/S1/P388. (Conference Contribution - Abstract)
  • Preiser, J-C., Jamaludin, U., Docherty, P.D., Chase, J.G., Le Compte, A.J., Shaw, G.M. and Desaive, T. (2011) Enteral nutrition-associated incretin effect in the critically ill. Gothenburg, Sweden: 33rd Excellence in Science, Practice and Education in Nutrition Congress (ESPEN), 3-6 Sep 2011. In Clinical Nutrition Supplements 6(1) 3. http://dx.doi.org/10.1016/S1744-1161(11)70007-2. (Conference Contribution - Abstract)
  • Signal, M., Le Compte, A.J., Chase, J.G. and Shaw, G.M. (2011) Glycaemic Levels in Critically Ill Patients: Is Normoglycemia and Low Variability Associated With Improved Outcomes. San Francisco, CA, USA: 11th Annual Diabetes Technology Meeting (DTM2011), 27-29 Oct 2011. (Conference Contribution - Abstract)
  • Fisk, L.M., Chase, J.G., Le Compte, A.J. and Shaw, G.M. (2011) Glycemic Control Protocol Comparison using Virtual Trials. San Francisco, CA, USA: 11th Annual Diabetes Technology Meeting (DTM2011), 2011. (Conference Contribution - Abstract)
  • Penning, S., Le Compte, A.J., Preiser, J-C., Chase, J.G. and Desaive, T. (2011) Glycemic Variability, Hypoglycemia and Organ Failure in the Glucontrol Study. Brussels, Belgium: 10th National Day on Biomedical Engineering, 2 Dec 2011. (Conference Contribution - Abstract)
  • Pretty, C.G., Chase, J.G., Lin, J., Shaw, G.M., Le Compte, A.J., Razak, N. and Parente, J.D. (2011) Impact of glucocorticoids on insulin resistance in the critically ill. Computer Methods and Programs in Biomedicine 102(2): 172-180. http://dx.doi.org/10.1016/j.cmpb.2010.08.004. (Journal Article)
  • Pretty, C.G., Le Compte, A.J., Chase, J.G., Lin, J. and Shaw, G.M. (2011) Impact of metoprolol on insulin sensitivity in the ICU. Milan, Italy: 18th World Congress of the International Federation of Automatic Control (IFAC 2011), 28 Aug-2 Sep 2011. 6pp. http://dx.doi.org/10.3182/20110828-6-IT-1002.01729. (Conference Contribution - Paper in published proceedings)
  • Ilyes, A., Havas, A., Nemedi, N.S., Benyo, B., Kovacs, L., LeCompte, A.J., Shaw, G.M. and Chase, J.G. (2011) Initial ICU Clinical Results Using SPRINT to Guide Insulin Infusions in a Hungarian Medical ICU. San Francisco, CA, USA: 11th Annual Diabetes Technology Meeting (DTM2011), 2011. (Conference Contribution - Abstract)
  • Chase, J.G., Le Compte, A.J., Preiser, J.C., Pretty, C.G., Moorhead, K.T., Penning, S., Shaw, G.M. and Desaive, T. (2011) Insulin Sensitivity, Its Variability and Glycemic Outcome: A model-based analysis of the difficulty in achieving tight glycemic control in critical care. Milan, Italy: 18th World Congress of the International Federation of Automatic Control (IFAC 2011), 28 Aug-2 Sep 2011. 6pp. http://dx.doi.org/10.3182/20110828-6-IT-1002.01281. (Conference Contribution - Paper in published proceedings)
  • Revie, J.A., Stevenson, D.J., Chase, J.G., Hann, C.E., Le Compte, A.J., Lambermont, B., Ghuysen, A., Kolh, P., Shaw, G.M. and Desaive, T. (2011) Model-based cardiovascular monitoring of large pore hemofiltration during endotoxic shock in pigs. Brussels, Belgium: 31st International Symposium on Intensive Care and Emergency Medicine (31st ISICEM), 22-25 Mar 2011. 1pp. http://ccforum.com/supplements/notes/ccv15s1-info.pdf. (Conference Contribution - Abstract)
  • Revie, J.A., Stevenson, D.J., Chase, J.G., Hann, C.E., Shaw, G.M., Le Compte, A.J., Lambermont, B.C., Ghuysen, A., Kolh, P. and Desaive, T. (2011) Model-based diagnosis of acute pulmonary embolism and septic shock in porcine trials. Christchurch, New Zealand: Health Research Society of Christchurch Annual Scientific Session, 15 Nov 2011. (Conference Contribution - Abstract)
  • Le Compte, A.J., Chase, J.G., Russell, G., Lynn, A., Hann, C.E., Shaw, G.M., Wong, X-W., Blakemore, A. and Lin, J. (2011) Modeling the glucose regulatory system in extreme preterm infants. Computer Methods and Programs in Biomedicine 102(3): 253-266. http://dx.doi.org/10.1016/j.cmpb.2010.05.006. (Journal Article)
  • Pretty, C.G., Lin, J., Le Compte, A.J., Shaw, G.M. and Chase, J.G. (2011) Pancreatic Insulin Secretion in Critically Ill Patients. San Francisco, CA, USA: 11th Annual Diabetes Technology Meeting (DTM2011), 27-29 Oct 2011. (Conference Contribution - Abstract)
  • Chase, J.G., Le Compte, A.J., Preiser, J.C., Shaw, G.M., Penning, S. and Desaive, T. (2011) Physiological Modeling, Tight Glycemic Control and the ICU Clinician: What are models and how can they affect practice? Annals of Intensive Care 1(11): 8pp. http://dx.doi.org/10.1186/2110-5820-1-11. (Journal Article)
  • Evans, A., Shaw, G.M., Le Compte, A.J., Tan, C.S., Ward, L., Steel, J., Pretty, C.G., Pfeifer, L., Penning, S., Suhaimi, F., Signal, M., Desaive, T. and Chase, J.G. (2011) Pilot Proof of Concept Clinical Trials of Stochastic Targeted (STAR) Glycemic Control. Annals of Intensive Care 1(38): Online. http://dx.doi.org/10.1186/2110-5820-1-38. (Journal Article)
  • Penning, S., Le Compte, A.J., Massion, P., Moorhead, K.T., Preiser, J.C., Shaw, G.M., Desaive, T. and Chase, J.G. (2011) Pilot Trials of STAR Target to Range Glycemic Control. Berlin, Germany: 24th ESICM LIVES Annual Congress, 1-5 Oct 2011. In Intensive Care Medicine 37(Supplement 1) S100. http://dx.doi.org/10.1007/s00134-011-2322-1. (Conference Contribution - Abstract)
  • Stevenson, D.J., Revie, J.A., Chase, J.G., Hann, C.E., Le Compte, A.J., Shaw, G.M., Lambermont, B., Kolh, P. and Desaive, T. (2011) Pulmonary embolism diagnostics from the driver function. Brussels, Belgium: 31st International Symposium on Intensive Care and Emergency Medicine (31st ISICEM), 22-25 Mar 2011. 1pp. http://ccforum.com/content/15/S1/P18. (Conference Contribution - Abstract)
  • Shaw, G.M., Le Compte, A.J., Evans, A., Tan, C.S., Steel, L., Ward, L., Pretty, C.G., Penning, S., Desaive, T. and Chase, J.G. (2011) Safety and Performance of Stochastic Targeted (STAR) Glycemic Control of Insulin and Nutrition - First Pilot Results. Berlin, Germany: 24th ESICM LIVES Annual Congress, 1-5 Oct 2011. In Intensive Care Medicine 37(Supplement 1) S99. http://dx.doi.org/10.1007/s00134-011-2322-1. (Conference Contribution - Abstract)
  • Shaw, G.M., Le Compte, A.J., Evans, A., Tan, C.S., Steel, J., Ward, L., Pretty, C.G., Penning, S., Desaive, T. and Chase, J.G. (2011) Safety and Performance of Stochastic Targeted (STAR) TGC of Insulin and Nutrition. Hunter Valley, Australia: 5th International Conference on Safety, Quality, Audit & Outcomes Research in Intensive Care (SQAO 2011), 1-3 Aug 2011. (Conference Contribution - Abstract)
  • Signal, M., LeCompte, A.J., Harris, D., Weston, P., Harding, J. and Chase, J.G. (2011) Sensitivity of Recalibrated Continuous Glucose Monitor Data. San Francisco, CA, USA: 11th Annual Diabetes Technology Meeting (DTM2011), 27-29 Oct 2011. (Conference Contribution - Abstract)
  • Chase, J.G., Le Compte, A.J., Suhaimi, F., Shaw, G.M., Lynn, A., Lin, J., Pretty, C.G., Razak, N.N., Parente, J.D., Hann, C.E., Preiser, J-C. and Desaive, T. (2011) Tight Glycemic Control in Critical Care - The leading role of insulin sensitivity and patient variability - A review and model-based analysis. Computer Methods and Programs in Biomedicine 102(2): 156-171. http://dx.doi.org/10.1016/j.cmpb.2010.11.006. (Journal Article)
  • Chase, J.G., Le Compte, A.J., Evans, A., Ward, L., Steel, J., Tan, C-S., Pretty, C.G., Penning, S., Desaive, T. and Shaw, G.M. (2011) Tight Glycemic Control in Intensive Care: From engineering to clinical practice change. Budapest, Hungary: 5th European Conference of IFMBE for Medical and Biological Engineering (MBEC), 14-18 Sep 2011. (Conference Contribution - Paper in published proceedings)
  • Suhaimi, F., Le Compte, A.J., Penning, S., Pretty, C.G., Preiser, J.C., Shaw, G.M., Desaive, T. and Chase, J.G. (2011) Validation of a virtual patient and virtual trials method for accurate prediction of TGC protocol performance. Brussels, Belgium: 31st International Symposium on Intensive Care and Emergency Medicine (31st ISICEM), 22-25 Mar 2011. In Critical Care 15(Supplement 1) P393. http://ccforum.com/supplements/notes/ccv15s1-info.pdf. (Conference Contribution - Abstract)
  • Lin, J., Razak, N.N., Chase, J.G., Suhaimi, F., Jamaluddin, U., Le Compte, A.J., Parente, J.D. and Shaw, G.M. (2010) A Highly Predictive Metabolic Model For Glycemic Control of Critically Ill Patients. Christchurch, New Zealand: Health Research Society of Canterbury (HRSC) Clinical Meeting, 23 Sep 2010. (Conference Contribution - Abstract)
  • Le Compte, A.J. (2010) Blood glucose control in Neonatal Intensive Care using stochastic targeted control. Auckland, New Zealand: Perinatal Society of New Zealand 30th Annual Scientific Meeting, 29 Oct 2010. (Conference Contribution - Oral presentation)
  • Le Compte, A.J., Lee, D.S., Chase, J.G., Lin, J., Lynn, A. and Shaw, G.M. (2010) Blood Glucose Prediction Using Stochastic Modeling in Neonatal Intensive Care. IEEE Transactions on Biomedical Engineering 57(3): 509-518. http://dx.doi.org/10.1109/TBME.2009.2035517. (Journal Article)
  • Signal, M., Pretty, C.G., Chase, J.G., Le Compte, A.J. and Shaw, G.M. (2010) Continuous Glucose Monitors and the Burden of Tight Glycemic Control in Critical Care: Can they Cure the Time Cost? Journal of Diabetes Science and Technology (JoDST) 4(3): 625-635. (Journal Article)
  • Signal, M., Pretty, C.G., LeCompte, A.J., Shaw, G.M. and Chase, J.G. (2010) Continuous Glucose Monitors and Tight Glycaemic Control in Intensive Care: An In-Silico Proof of Concept Analysis. Coventry, UK: UKACC International Conference on CONTROL 2010, 7-10 Sep 2010. (Conference Contribution - Full conference paper)
  • Razak, N.N., Lin, J., Chase, J.G., Shaw, G.M., Pretty, C.G., LeCompte, A.J., Suhaimi, F.M. and Jamaludin, U. (2010) Glargine as a Basal Insulin Supplement in Recovering Critically Ill Patients - An In Silico Study. Coventry, UK: UKACC International Conference on CONTROL 2010, 7-10 Sep 2010. (Conference Contribution - Full conference paper)
  • Pretty, C.G., Chase, J.G., Le Compte, A.J., Shaw, G.M. and Signal, M. (2010) Hypoglycemia Detection in Critical Care Using Continuous Glucose Monitors: An in Silico Proof of Concept Analysis. Journal of Diabetes Science and Technology (JoDST) 4(1): 15-24. (Journal Article)
  • LeCompte, A.J., Chase, J.G., Shaw, G.M., Lin, J. and Lynn, A. (2010) Impact of variation in patient response on model-based control of glycaemia in critically ill patients. Coventry, UK: UKACC International Conference on CONTROL 2010, 7-10 Sep 2010. (Conference Contribution - Full conference paper)
  • LeCompte, A.J., Ramachandran, M., Goldberg, P.A., Honiden, S., Inzucchi, S.E. and Chase, J.G. (2010) In silico Analysis and Optimization of the Yale Insulin Infusion Protocol. Orlando, FL, USA: 70th Scientific Sessions of the American Diabetes Association (ADA 2010), 25-29 Jun 2010. (Conference Contribution - Abstract)
  • Lin, J., Razak, N.N., Pretty, C.G., LeCompte, A.J., Docherty, P.D., Parente, J.D., Shaw, G.M., Hann, C.E. and Chase, J.G. (2010) Intensive Control Insulin-Nutrition-Glucose Model Validated in Critically Ill Patients. Coventry, UK: UKACC International Conference on CONTROL 2010, 7-10 Sep 2010. (Conference Contribution - Full conference paper)
  • Lin, J., Jamaludin, U., Docherty, P.D., Razak, N.N., LeCompte, A.J., Pretty, C.G., Hann, C.E., Shaw, G.M. and Chase, J.G. (2010) Modeled Insulin Sensitivity and Interstitial Insulin Action from a Pilot Study of Dynamic Insulin Sensitivity Tests. Coventry, UK: UK International Conference on CONTROL 2010, 7-10 Sep 2010. (Conference Contribution - Full conference paper)
  • Razak, N.N., Lin, J., Chase, J.G., Pretty, C.G., LeCompte, A.J., Suhaimi, F., Jamaluddin, U. and Shaw, G.M. (2010) Monte Carlo Analysis Of A Glycaemic Control Protocol In Less Acute Wards. Bethesda, MD, USA: 10th Annual Diabetes Technology Meeting (DTM2010), 11-13 Nov 2011. (Conference Contribution - Abstract)
  • Chase, J.G., Pretty, C.G., Pfeifer, L., Shaw, G.M., Preiser, J-C., Le Compte, A.J., Lin, J., Hewett, D., Moorhead, K.T. and Desaive, T. (2010) Organ Failure and Tight Glycemic Control in the SPRINT Study. Critical Care 14: R154. http://dx.doi.org/10.1186/cc9224. (Journal Article)
  • LeCompte, A.J., Penning, S., Moorhead, K.T., Massion, P., Preiser, J-C., Shaw, G.M., Desaive, T. and Chase, J.G. (2010) Pilot Trials of the STAR TGC Protocol in a Cardiac Surgery ICU. Bethesda, MD, USA: 10th Annual Diabetes Technology Meeting (DTM2010), 11-13 Nov 2010. In Proceedings of the 10th Annual Diabetes Technology Meeting (DTM2010) (Conference Contribution - Abstract)
  • Preiser, J-C., Chase, J.G., Pretty, C.G., Pfeiffer, L., Shaw, G.M., Le Compte, A.J., Lin, J., Hewett, D. and Desaive, T. (2010) Reduced Organ Failure with Effective Glycemic Control. Barcelona, Spain: 23rd European Society of Intensive Care Medicine Annual Congress (ESICM), 10-13 Oct 2010. (Conference Contribution - Abstract)
  • Preiser, J-C., Suhaimi, F., Chase, J.G., Le Compte, A.J., Shaw, G.M., Pretty, C.G., Lin, J., Hann, C.E. and Desaive, T. (2010) The Critical Role of Carbohydrate Administration in Safe, Effective TGC. Nice, France: 32nd Excellence in Science, Practice and Education in Nutrition 2010 - 32nd Congress of Clinical Nutrition and Metabolism (ESPEN 2010), 5-8 Sep 2010. (Conference Contribution - Abstract)
  • Preiser, J.C., Suhaimi, F., Chase, J.G., Le Compte, A.J., Shaw, G.M., Pretty, C.G., Lin, J., Hann, C.E. and Desaive, T. (2010) The critical role of carbohydrate administration in safe, effective TGC. Clinical Nutrition Supplements 5(2): 111-112. (Journal Article)
  • Suhaimi, F., Le Compte, A.J., Preiser, J-C., Massion, P., Radermecker, R., Pretty, C.G., Shaw, G.M., Desaive, T. and Chase, J.G. (2010) Tight Glycaemic control and nutrition: A comparison of two protocols. University of Otago, Christchurch, New Zealand: Centre for Bio-Engineering One Day Conference, 10 Nov 2010. (Conference Contribution - Abstract)
  • Penning, S., Le Compte, A.J., Desaive, T. and Chase, J.G. (2010) Tight Glycemic Control Models for Critically Ill Patients in Intensive Care Units. Brussels, Belgium: NCBME National Day on Bio-Engineering Conference, 26 Nov 2010. (Conference Contribution - Abstract)
  • Suhaimi, F., Chase, J.G., Le Compte, A.J., Preiser, J-C., Lin, J., Desaive, T. and Shaw, G.M. (2010) Validation of a Model-based Virtual Trials Method for Tight Glycaemic Control in Intensive Care. University of Otago, Christchurch, New Zealand: Centre for Bio-Engineering One Day Conference, 10 Nov 2010. (Conference Contribution - Abstract)
  • Suhaimi, F.M., Chase, J.G., LeCompte, A.J., Preiser, J-C., Lin, J. and Shaw, G.M. (2010) Validation of a Model-based Virtual Trials Method for Tight Glycemic Control in Intensive Care. Coventry, UK: UKACC International Conference on CONTROL 2010, 7-10 Sep 2010. In Biomedical Engineering Online 9 84. http://dx.doi.org/10.1186/1475-925X-9-84. (Conference Contribution - Paper in published proceedings)
  • Chase, J.G., Suhaimi, F., Penning, S., Preiser, J-C., Le Compte, A.J., Lin, J., Pretty, C.G., Shaw, G.M., Moorhead, K.T. and Desaive, T. (2010) Validation of a Model-based Virtual Trials Method for Tight Glycemic Control in Intensive Care. BioMedical Engineering OnLine 9(84) http://dx.doi.org/10.1186/1475-925X-9-84. (Journal Article)
  • Suhaimi, F., Chase, J.G., Preiser, J-C., Le Compte, A.J., Lin, J., Pretty, C.G., Shaw, G.M. and Desaive, T. (2010) Validation of a virtual trial method for tight glycemic control in intensive care. Christchurch, New Zealand: Health Research Society of Canterbury (HRSC) Clinical Meeting, 23 Sep 2010. (Conference Contribution - Abstract)
  • Suhaimi, F., Le Compte, A.J., Preiser, J-C., Shaw, G.M., Massion, P., Radermecker, R.P., Pretty, C.G., Lin, J., Desaive, T. and Chase, J.G. (2010) What Makes Tight Glycemic Control Tight? The Impact of Variability and Nutrition in Two Clinical Studies. Journal of Diabetes Science and Technology (JoDST) 4(2): 284-298. (Journal Article)
  • Chase, J.G., LeCompte, A.J., Steel, J., Ward, L.M., Evans, A., Tan, C., Lynn, A. and Shaw, G.M. (2010) What went wrong? The Importance of Better Human Factors. Bethesda, MD, USA: 10th Annual Diabetes Technology Meeting (DTM2010), 11-13 Nov 2010. In Proceedings of the 10th Annual Diabetes Technology Meeting (DTM2010) (Conference Contribution - Abstract)
  • Wong, X.W., Chase, J.G., LeCompte, A.J., Hann, C.E., Lin, J. and Shaw, G.M. (2009) An adaptive clinical Type 1 diabetes control protocol to optimise conventional self-monitoring blood glucose and multiple daily injection therapy. International Journal of Adaptive Signal Processing and Control 23(5): 408-434. http://dx.doi.org/10.1002/acs.1069. (Journal Article)
  • LeCompte, A.J., Chase, J.G., Lynn, A., Hann, C.E., Shaw, G.M. and Lin, J. (2009) Blood Glucose Control in Neonatal Intensive Care with Model-Based Controllers. Aalborg, Denmark: 7th IFAC Symposium on Modelling and Control in Biomedical Systems (MCBMS 09), 12-14 Aug 2009. In Proceedings of the 7th IFAC Symposium on Modelling and Control in Biomedical Systems 19-24. (Conference Contribution - Paper in published proceedings)
  • LeCompte, A.J., Lynn, A.M., Chase, J.G., Shaw, G.M., Lin, J., Hann, C.E. and Lee, D.S. (2009) Blood Glucose Control in Preterm VLBW Infants Using Model-based Methods. Christchurch, New Zealand: 29th Annual Scientific Meeting of the Perinatal Society of New Zealand, 16 Oct 2009. (Conference Contribution - Full conference paper)
  • LeCompte, A.J., Chase, J.G., Lynn, A., Hann, C.E., Shaw, G.M., Wong, X.W. and Lin, J. (2009) Blood Glucose Controller for Neonatal Intensive Care: Virtual trials development and 1st clinical trials. Journal of Diabetes Science and Technology 3(5): 1066-1081. http://www.journalofdst.org/September2009/. (Journal Article)
  • Pretty, C., Chase, J.G., Lin, J., Shaw, G., LeCompte, A., Razak, N. and Parente, J. (2009) Corticosteroids and Insulin Resistance in the ICU. Aalborg, Denmark: 7th IFAC Symposium on Modelling and Control in Biomedical Systems (MCBMS 09), 12-14 Aug 2009. In Proceedings of the 7th IFAC Symposium on Modelling and Control in Biomedical Systems 7(1) 25-30. (Conference Contribution - Paper in published proceedings)
  • Lin, J., Parente, J.D., Chase, J.G., Shaw, G.M., Blakemore, A., Le Compte, A.J., Pretty, C., Razak, N., Lee, D., Hann, C.E. and Wang, S.H. (2009) Development of a Model-Based Clinical Sepsis Biomarker for Critically Ill Patients. Aalborg, Denmark: 7th IFAC Symposium on Modelling and Control in Biomedical Systems (MCBMS 09), 12-14 Aug 2009. (Conference Contribution - Full conference paper)
  • Pretty, C.G., Chase, J.G., Lin, J., Shaw, G.M., LeCompte, A.J., Razak, N., Parente, J. and Suhaimi, F. (2009) Glucocorticoids, Insulin Sensitivity and Tight Glycaemic Control in the ICU. San Francisco, CA, USA: 9th Annual Diabetes Technology Meeting, 5-7 Nov 2009. (Conference Contribution - Abstract)
  • Wong, X.W., Chase, J.G., Shaw, G.M., Lin, J., LeCompte, A.J. and Hann, C.E. (2009) In Silico Monte Carlo Virtual Trials of a Model-Based Adaptive Type 1 Diabetes Mellitus Control Protocol. Bethesda, MD, USA: 8th Annual Diabetes Technology Meeting, 13-15 Nov 2008. In Journal of Diabetes Science and Technology 3(2) A177. (Conference Contribution - Abstract)
  • LeCompte, A.J., Lynn, A., Chase, J.G., Lee, D.S., Wong, X.W., Lin, J. and Hann, C.E. (2009) Model-based targeted control with stochastic forecasting for regulation of glycemia in ELBW neonates. San Francisco, CA, USA: 9th Annual Diabetes Technology Meeting, 5-7 Nov 2009. (Conference Contribution - Abstract)
  • Le Compte, A.J. (2009) Modelling the Glucose-Insulin Regulatory System for Glycaemic Control in Neonatal Intensive Care. PhD, University of Canterbury, Christchurch, New Zealand. (Thesis - Doctor of Philosophy)
  • Le Compte, A.J., Lynn, A., Chase, J.G., Shaw, G.M., Russel, G., Blakemore, A., Lee, D.S. and Wong, X.W. (2009) Neonatal Glycemic Control: Model Validation and In Silico Virtual Patient Trials. Bethesda, MD, USA: 8th Annual Diabetes Technology Meeting, 13-15 Nov 2008. In Journal of Diabetes Science and Technology 3(2) A100. (Conference Contribution - Abstract)
  • Lin, J., Razak, N.N., Chase, G., Wong, J., Pretty, C., Parente, J.D., LeCompte, A.J., Suhaimi, F.M., Shaw, G. and Hann, C. (2009) The Effect of Glargine as Basal Insulin Support for Recovering Critically Ill and High Dependency Unit Patients: An In Silico Study. Aalborg, Denmark: 7th IFAC Symposium on Modelling and Control in Biomedical Systems (MCBMS 09), 12-14 Aug 2009. In Proceedings of the 7th IFAC Symposium on Modelling and Control in Biomedical Systems 7(1) 49-54. (Conference Contribution - Paper in published proceedings)
  • Chase, J.G., LeCompte, A.J., Pretty, C.G., Lynn, A., Shaw, G.M., Lin, J., Razak, N. and Parente, J. (2009) The Impact of Insulin Sensitivity Variability and Dynamics on Tight Glycemic Control in Neonatal and Adult Intensive Care. New Orleans, LA, USA: American Diabetes Association (ADA) 69th Scientific Sessions, 5-9 Jun 2009. In Diabetes 48(Suppl. 1) A161-A162. (Conference Contribution - Abstract)
  • Chase, J.G., LeCompte, A., Shaw, G.M., Lin, J., Pretty, C., Razak, N., Parente, J., Lynn, A., Hann, C.E. and Suhaimi, F. (2009) Tight Glycemic Control - The Leading Role of Insulin Sensitivity in Determining Efficacy and Thus Outcome. Aalborg, Denmark: 7th IFAC Symposium on Modelling and Control in Biomedical Systems (MCBMS 09), 12-14 Aug 2009. (Conference Contribution - Full conference paper)
  • LeCompte, A.J., Lynn, A., Chase, J.G., Shaw, G.M., Pretty, C.G., Mayntzhusen, K., Docherty, P.D. and Parente, J. (2009) Tight Glycemic Control in the Neonatal Intensive Care Unit - Proof of Concept Pilot Trials. New Orleans, LA, USA: American Diabetes Association (ADA) 69th Scientific Sessions, 5-9 Jun 2009. In Diabetes 58(Suppl. 1) A162. (Conference Contribution - Abstract)
  • Suhaimi, F., Le Compte, A.J., Preiser, J-C., Massion, P., Rademecker, R., Pretty, C.G., Shaw, G.M., Desaive, T. and Chase, J.G. (2009) What makes TGC protocols "T" (tight)? An analysis of data from 2 studies. San Francisco, CA, USA: 9th Annual Diabetes Technology Meeting, 5-7 Nov 2009. (Conference Contribution - Abstract)
  • Wong, J., Chase, J.G., Hann, C.E., Shaw, G.M., Lotz, T.F., Lin, J. and Le Compte, A.J. (2008) A Subcutaneous Insulin Pharmacokinetic Model for Computer Simulation in a Diabetes Decision Support Role: Validation and Simulation. Journal of Diabetes Science and Technology 2(4): 672-680. (Journal Article)
  • LeCompte, A.J., Chase, J.G., Shaw, G.M., Lynn, A. and Russell, G. (2008) Blood glucose modelling and control for pre-term infants. Christchurch, New Zealand: 2008 Engineering & Physical Sciences in Medicine and Australian Biomedical Engineering Conference, 16-20 Nov 2008. (Conference Contribution - Abstract)
  • Razak, N., Parente, J., Lin, J., Chase, J.G., Hann, C.E., Pretty, C.G., Le Compte, A.J. and Shaw, G.M. (2008) Clinical Data Validation Of A New, Physiologically Relevant Critical Care Glycaemic Control Model. Christchurch, New Zealand: 2008 Engineering & Physical Sciences in Medicine and Australian Biomedical Engineering Conference, 16-20 Nov 2008. (Conference Contribution - Abstract)
  • Wong, X.W., Chase, J.G., Hann, C.E., Lotz, T., Lin, J., Le Compte, A.J. and Shaw, G.M. (2008) Development of a Clinical Type 1 Diabetes Metabolic System Model and in Silico Simulation Tool. Journal of Diabetes Science and Technology 2(3): 424-435. (Journal Article)
  • Le Compte, A.J., Chisholm, G., Pretty, C.G., Chase, J.G., Shaw, G.M., Razak, N., Parente, J., Hann, C.E. and Lin, J. (2008) Drug Therapy And (Model-Based) Metabolic Markers: Is Tight Glucose Control In Critical Care Affected By Drug Choices. Christchurch, New Zealand: 2008 Engineering & Physical Sciences in Medicine and Australian Biomedical Engineering Conference, 16-20 Nov 2008. (Conference Contribution - Abstract)
  • Chase, J.G., Shaw, G.M., Blakemore, A., Wang, S., LeCompte, A.J., Wong, X.W., Lotz, T., Lin, J. and Hann, C.E. (2008) High(er) Insulin Sensitivity Rules Out Sepsis in Critical Care. San Francisco, CA, USA: American Diabetes Association 68th Scientific Sessions 2008, 6-10 Jun 2008. In Diabetes 57(Supplement 1) A23. (Conference Contribution - Paper in published proceedings)
  • Chase, J.G., Shaw, G.M., Blakemore, A., Wang, S., LeCompte, A.J., Wong, X.W., Lotz, T., Lin, J. and Hann, C.E. (2008) High(er) Insulin Sensitivity Rules Out Sepsis in Critical Care. San Francisco, CA, USA: American Diabetes Association (ADA) 68th Scientific Sessions Conference, 6-10 Jun 2008. 1pp. (Conference Contribution - Abstract)
  • Chase, J.G., Shaw, G., Le Compte, A., Lonergan, T., Willacy, M., Wong, X-W., Lin, J., Lotz, T., Lee, D. and Hann, C. (2008) Implementation and evaluation of the SPRINT protocol for tight glycaemic control in critically ill patients: a clinical practice change. Critical Care 12(2): R49. http://dx.doi.org/10.1186/cc6868. (Journal Article)
  • Wong, X.W., Chase, J.G., Hann, C.E., Lotz, T., Lin, J., Le Compte, A.J. and Shaw, G.M. (2008) In Silico Simulation of Long-Term Type 1 Diabetes Glycemic Control Treatment Outcomes. Journal of Diabetes Science and Technology 2(3): 436-449. (Journal Article)
  • Le Compte, A.J., Chase, J.G., Russel, G., Hann, C.E. and Shaw, G.M. (2008) Model-Based Blood Glucose Control for Neonatal Intensive Care. Auckland, New Zealand: NZBio 2008 Conference & Exposition, 30 Mar-2 Apr 2008. (Conference Contribution - Full conference paper)
  • Blakemore, A., Wang, S., Le Compte, A.J., Wong, X.W., Shaw, G.M., Lotz, T., Hann, C.E. and Chase, J.G. (2008) Model-Based Insulin Sensitivity as a Sepsis Diagnostic in Critical Care. Journal of Diabetes Science and Technology 2(3): 468-477. (Journal Article)
  • Lotz, T.F., Chase, J.G., McAuley, K.A., Shaw, G.M., Wong, X.W., Lin, J., Lecompte, A., Hann, C.E. and Mann J.I. (2008) Monte Carlo analysis of a new model-based method for insulin sensitivity testing. Computer Methods and Programs in Biomedicine 89(3): 215-225. http://dx.doi.org/10.1016/j.cmpb.2007.03.007. (Journal Article)
  • Lin, J., Lee, D.S., Chase, J.G., Shaw, G.M., LeCompte, A.J., Lotz, T., Wong, X.W., Lonergan, T. and Hann C.E. (2008) Stochastic modelling of insulin sensitivity and adaptive glycemic control for critical care. Computer Methods and Programs in Biomedicine 89(2): 141-152. http://dx.doi.org/10.1016/j.cmpb.2007.04.006. (Journal Article)
  • Chase, J.G., Chen, H., Sirisena, H., Shaw, G., Wong, X-W., Hann, C., Le Compte, A., Lin, J. and Lotz, T. (2007) Hierarchical Real-Time Filtering for Continuous Glucose Sensor Data. Diabetes Science and Technology 1(2): A21. (Journal Article)
  • Lotz, T., Chase, J.G., McAuley, K.A., Shaw, G.M., Wong, X-.W., Lin, J. and Le Compte, A. (2007) Highly correlated model-based testing of insulin sensitivity - initial results for a proposed low-intensity test. Diabetes Science and Technology 1(2): A103. (Journal Article)
  • Chase, J.G., Shaw, G.M., Lotz, T., Le Compte, A., Wong, J., Lin, J., Lonergan, T., Willacy, M. and Hann, C.E. (2007) Model-Based Insulin and Nutrition Administration for Tight Glycaemic Control in Critical Care. Current Drug Delivery (CDD) 4(4): 283-296. (Journal Article)
  • Chase, J.G., Shaw, G.M., Le Compte, A., Lee, D.S., Lonergan, T., Willacy, M., Wong, X.W., Lin, J., Lotz, T. and Hann, C. (2007) Tight Glycaemic Control in Critical Care Using Insulin and Nutrition - the SPRINT Protocol. Diabetes Science and Technology 1(2): A22. (Journal Article)
  • Lonergan, T., Le Compte, A., Willacy, M., Chase, J.G., Shaw, G.M., Hann, C.E., Lotz, T., Lin, J. and Wong, X.W. (2006) A Pilot Study of the SPRINT Protocol for Tight Glycaemic Control in Critically Ill Patients. Diabetes Technology & Therapeutics 8(4): 449-462. http://dx.doi.org/10.1089/dia.2006.8.449. (Journal Article)
  • Lonergan, T., Le Compte, A., Willacy, M., Chase, J.G., Shaw, G.M., Wong, X-W., Lotz, T., Lin, J. and Hann, C.E. (2006) A Simple Insulin-Nutrition Protocol for Tight Glycemic Control in Critical Illness: Development and Protocol Comparison. Diabetes Technology & Therapeutics 8(2): 191-206. http://dx.doi.org/10.1089/dia.2006.8.191. (Journal Article)
  • Chase, J.G., Shaw, G.M., Hann, C.E., LeCompte, A., Lonergan, T., Willacy, M., Wong, X.W., Lin, J. and Lotz, T. (2006) Clinical Validation of a Model-based Glycaemic Control Design Approach and Comparison to Other Clinical Protocols. New York, NY, USA: 28th International Conference of IEEE Engineering in Medicine and Biology Society (EMBS 2006), 30 Aug-3 Sept 2006. In Proceedings of the 28th International Conference of IEEE Engineering in Medicine and Biology Society (EMBS 2006) 4pp. http://ieeexplore.ieee.org/xpl/conferences.jsp. (Conference Contribution - Paper in published proceedings)
  • Chase, J.G., Chen, H., Sirisena, H., Shaw, G., Wong, X-W., Hann, C., Le Compte, A., Lin, J. and Lotz, T. (2006) Hierarchical Real-Time Filtering for Continuous Glucose Sensor Data. Atlanta, GA, USA: 6th Annual Diabetes Technology Meeting of the Diabetes Technology Society, 2-4 Nov 2006. (Conference Contribution - Abstract)
  • Lotz, T., Chase, J.G., McAuley, K., Shaw, G., Wong, X-W., Lin, J. and Le Compte, A. (2006) Highly Correlated Model-Based Testing of Insulin Sensitivity - Initial Results for a Proposed Low-Intensity Test. Atlanta, GA, USA: 6th Annual Diabetes Technology Meeting of the Diabetes Technology Society, 2-4 Nov 2006. (Conference Contribution - Abstract)
  • Chase, J.G., Wong, J., Lin, J., Le Compte, A., Lotz, T., Lonergan, T., Willacy, M., Hann, C.E. and Shaw, G.M. (2006) Insulin + Nutrition control for tight critical care glycaemic regulation. Reims, France: 6th IFAC Symposium on Modelling and Control in Biomedical Systems (Including Biological Sciences) (MCBMS'06), 19-22 Sep 2006. In Modelling and Control in Biomedical Systems 2006 (including Biological Systems) 339-344. (Conference Contribution - Paper in published proceedings)
  • Shaw, G.M., Endre, Z., Le Compte, A., Jo, A., Chase, J.G. and Hann, C.E. (2006) Modeling Renal Function to Assess Markers of Acute Renal Failure. Christchurch, New Zealand: Australia New Zealand Intensive Care Society (ANZICS) New Zealand Region Annual Scientific Meeting, 5-7 Apr 2006. (Conference Contribution - Abstract)
  • Shaw, G.M., Chase, J.G., Wong, X.W., Lin, J., Lotz, T., Le Compte, A., Lonergan, T., Willacy, M. and Hann, C.E. (2006) The SPRINT Protocol for Tight Glycaemic Control. Christchurch, New Zealand: Australia-New Zealand Intensive Care Society (ANZICS) New Zealand Region Annual Scientific Meeting, 5-7 Apr 2006. (Conference Contribution - Abstract)
  • Chase, J.G., Shaw, G., Le Compte, A., Lee, D., Lonergan, T., Willacy, M., Wong, X-W., Lin, J., Lotz, T. and Hann, C. (2006) Tight Glycaemic Control in Critical Care Using Insulin and Nutrition - the SPRINT Protocol. Atlanta, GA, USA: 6th Annual Diabetes Technology Meeting of the Diabetes Technology Society, 2-4 Nov 2006. (Conference Contribution - Abstract)
  • Shaw, G.M., Chase, J.G., Wong, X.W., Lin, J., Lotz, T., Le Compte, A.J., Lonergan, T., Willacy, M. and Hann, C.E. (2006) Tight Glycaemic Control with a Variable Insulin and Nutrition Protocol. Anaesthesia and Intensive Care 34(4): 543. (Journal Article)
  • Shaw, G.M., Chase, J.G., Wong, X.W., Lin, J., Lotz, T., Le Compte, A., Lonergan, T., Willacy, M. and Hann, C.E. (2006) Tight glycaemic control with a variable insulin in nutrition protocol. Adelaide, Australia: Australia-New Zealand College of Anaesthesia Annual Scientific Meeting (ANZCA 2006), 13-17 May 2006. (Conference Contribution - Abstract)
  • Chase, J.G., Lonergan, T., Le Compte, A.J., Willacy, M.B., Shaw, G.M., Wong, X.W., Lin, J., Lotz, T. and Hann, C. (2005) Tight Glucose Control in Critically Ill Patients Using a Specialized Insulin-Nutrition Table. Singapore: 12th International Conference on Biomedical Engineering, 7-10 Dec 2005. 2A5-03 4 pp. http://www.icbme.org/. (Conference Contribution - Paper in published proceedings)